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Axel Petzold
Researcher at UCL Institute of Neurology
Publications - 353
Citations - 16467
Axel Petzold is an academic researcher from UCL Institute of Neurology. The author has contributed to research in topics: Optic neuritis & Multiple sclerosis. The author has an hindex of 63, co-authored 326 publications receiving 13047 citations. Previous affiliations of Axel Petzold include National Institute for Health Research & Veterans Health Administration.
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Journal ArticleDOI
Neurofilaments as biomarkers in neurological disorders
Michael Khalil,Charlotte E. Teunissen,Markus Otto,Fredrik Piehl,Maria Pia Sormani,Thomas Gattringer,Christian Barro,Ludwig Kappos,Manuel Comabella,Franz Fazekas,Axel Petzold,Kaj Blennow,Kaj Blennow,Henrik Zetterberg,Jens Kuhle +14 more
TL;DR: How technological advances have enabled the detection of neurofilament proteins in the blood is considered, and how these proteins consequently have the potential to be easily measured biomarkers of neuroaxonal injury in various neurological conditions are discussed.
Journal ArticleDOI
A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking
Charlotte E. Teunissen,Axel Petzold,Jeffrey Bennett,Frode S. Berven,Lou Brundin,Manuel Comabella,Diego Franciotta,Jette L. Frederiksen,John O. Fleming,Roberto Furlan,Rogier Q. Hintzen,S Hughes,M. H. Johnson,Eva Krasulova,Jens Kuhle,Maria Chiara Magnone,Cecilia Rajda,Konrad Rejdak,Hollie Schmidt,Vincent Van Pesch,Emmanuelle Waubant,Christian Wolf,Gavin Giovannoni,Bernhard Hemmer,Hayrettin Tumani,Florian Deisenhammer +25 more
TL;DR: A consensus report on recommendations for CSF collection and biobanking is presented, formed by the BioMS-eu network forCSF biomarker research in multiple sclerosis, and focuses on CSf collection procedures, preanalytical factors, and high-quality clinical and paraclinical information.
Journal ArticleDOI
Neurofilament phosphoforms: surrogate markers for axonal injury, degeneration and loss.
TL;DR: This review on the role of neurofilaments as surrogate markers for axonal degeneration in neurological diseases provides a brief background to protein synthesis, assembly, function and degeneration.
Journal ArticleDOI
Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis
Axel Petzold,Johannes F. de Boer,Sven Schippling,Patrik Vermersch,Randy H. Kardon,Ari J. Green,Peter A. Calabresi,Chris H. Polman +7 more
TL;DR: The estimated RNFL thinning in patients with MS is greater than the extent expected in normal ageing, probably because of retrograde trans-synaptic degeneration and progressive loss of retinal ganglion cells, in addition to the more pronounced thinning caused by optic neuritis if present.
Journal ArticleDOI
The OSCAR-IB consensus criteria for retinal OCT quality assessment.
Prejaas Tewarie,Lisanne J. Balk,Fiona Costello,Ari J. Green,Roland Martin,Sven Schippling,Axel Petzold +6 more
TL;DR: This study presents the first validated consensus QC criteria for retinal OCT reading in MS, and suggests the OSCAR-IB QC criteria to be considered in the context of multicentre studies and trials in MS.