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Ayano Kondo

Researcher at University of Pennsylvania

Publications -  12
Citations -  1364

Ayano Kondo is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Cell type & Cellular differentiation. The author has an hindex of 5, co-authored 10 publications receiving 822 citations.

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Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

TL;DR: It is inferred that inherited kidney diseases that arise from distinct genetic mutations but share the same phenotypic manifestation originate from the same differentiated cell type, and that the collecting duct in kidneys of adult mice generates a spectrum of cell types through a newly identified transitional cell.
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Subepithelial telocytes are an important source of Wnts that supports intestinal crypts

TL;DR: Subepithelial telocytes are identified as a source of Wnt signals that enable proliferation and differentiation of intestinal stem cells, an essential function for maintenance of the intestinal epithelium.
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Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets.

TL;DR: In this article, the authors profile open chromatin and gene expression in developing and adult mouse kidneys at single cell resolution and reveal key cell type-specific transcription factors and major gene-regulatory circuits for kidney cells.
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Emerging diverse roles of telocytes.

TL;DR: The discovery of telocytes, their physical properties, distribution and function, focusing on recent developments in the functional analysis of Foxl1-positive telocytes in the intestinal stem cell niche, and, finally, the current challenges of studying telocytes as a distinct cell type are discussed.