Author
B.C. Das
Bio: B.C. Das is an academic researcher from Institut de Chimie des Substances Naturelles. The author has contributed to research in topics: Absolute configuration & Methyl acrylate. The author has an hindex of 12, co-authored 22 publications receiving 437 citations.
Papers
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TL;DR: In this article, 14 depsipeptides have been isolated from the culture medium of a strain of Metarhizium anisopliae and five of them were identified as known destruxins A, B, C, D and desmethyldestruxin B.
129 citations
58 citations
TL;DR: In this article, a route to 1,2-dihydropyridines N1-substituted with chiral auxiliaries has been developed starting from commercially available chiral amines.
37 citations
TL;DR: The structure of deplancheine 5, an indoloquinolizidine alkaloid of a novel type, has been established from its spectral properties and also by an orginal synthesis as discussed by the authors.
30 citations
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1,143 citations
TL;DR: Stereoselective Addition to N-Activated Pyridines James A. Bull, Guillaume Pelletier,† and Andre ́ B. Charette are credited for this work.
Abstract: Stereoselective Addition to N-Activated Pyridines James A. Bull,‡ James J. Mousseau, Guillaume Pelletier,† and Andre ́ B. Charette*,† †Department of Chemistry, Universite ́ de Montreál, P.O. Box 6128, Station Downtown, Montreál, Queb́ec, Canada H3C 3J7 ‡Department of Chemistry, Imperial College London, South Kensington, London SW7 2AZ, U.K. Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
679 citations
TL;DR: This review covers the literature on simple indole alkaloid and those with a nonrearranged monoterpenoid unit and newly isolated alkaloids, structure determinations, total syntheses and biological activities.
531 citations
TL;DR: All relevant safety data of this fungus are summarized, and M. anisopliae is considered to be safe with minimal risks to vertebrates, humans and the environment.
Abstract: The entomopathogenic fungus Metarhizium anisopliae (Metschn.) Sorokin is widely used for biocontrol of pest insects, and many commercial products are on the market or under development. The aim of this review is to summarise all relevant safety data of this fungus, which are necessary for the commercialisation and registration process. The review contains the following sections: (1) identity, (2) biological properties (history, natural occurrence and geographical distribution, host range, mode of action, production of metabolites/toxins, effect of environmental factors), (3) methods to determine and quantify residues, (4) fate and behaviour in the environment (mobility and persistence in air, water and soil), (5) effects on non-target organisms (microorganisms, plants, soil organisms, aquatic organisms, predators, parasitoids, honey bees, earth worms, etc.), (6) effects on vertebrates (fish, amphibia, reptiles, and birds), and (7) effects on mammals and human health (allergy, pathogenicity/toxici...
449 citations
TL;DR: Understanding the mechanisms of pathogenesis have parallels with those of some plant-pathogenic fungi, particularly in the areas of formation of an infection structure, entry into the host and toxin-mediated host death, will provide a rational basis for strain selection and improvement.
401 citations