B
B.E. de Pauw
Researcher at Radboud University Nijmegen
Publications - 109
Citations - 7458
B.E. de Pauw is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Aspergillosis & Neutropenia. The author has an hindex of 35, co-authored 109 publications receiving 7305 citations. Previous affiliations of B.E. de Pauw include University of California, Los Angeles & European Organisation for Research and Treatment of Cancer.
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Journal ArticleDOI
Defining Opportunistic Invasive Fungal Infections in Immunocompromised Patients with Cancer and Hematopoietic Stem Cell Transplants: An International Consensus
Sibel Ascioglu,John H. Rex,B.E. de Pauw,John E. Bennett,J. Bille,F. Crokaert,David W. Denning,J.P. Donnelly,J. E. Edwards,Z. Erjavec,D. Fiere,O. Lortholary,Johan Maertens,Jacques F. Meis,Thomas F. Patterson,J. Ritter,D. Selleslag,Palak Shah,David A. Stevens,Thomas J. Walsh +19 more
TL;DR: A set of research-oriented definitions for the IFIs most often seen and studied in immunocompromised patients with cancer is proposed and three levels of probability are proposed: "proven," "probable," and "possible."
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Candidemia in Cancer Patients: A Prospective, Multicenter Surveillance Study by the Invasive Fungal Infection Group (IFIG) of the European Organization for Research and Treatment of Cancer (EORTC)
C. Viscoli,Corrado Girmenia,A. Marinus,Laurence Collette,P. Martino,Bernard Vandercam,Chantal Doyen,B. Lebeau,David Spence,Vladimir Krcmery,B.E. de Pauw,Françoise Meunier +11 more
TL;DR: Two multivariate analyses showed that mortality was associated with older age and severity of the underlying disease, and additional factors associated with mortality were allogeneic bone marrow transplantation, septic shock, and lack of antifungal prophylaxis.
Journal ArticleDOI
International Conference for the Development of a Consensus on the Management and Prevention of Severe Candidal Infections.
J E Jr Edwards,G. P. Bodey,R. A. Bowden,T. Buchner,B.E. de Pauw,Scott G. Filler,Mahmoud A. Ghannoum,M. Glauser,Raoul Herbrecht,C. A. Kauffman,S. Kohno,P. Martino,F. Meunier,Takeshi Mori,M. A. Pfaller,John H. Rex,Thomas R. Rogers,Robert H. Rubin,Joseph S. Solomkin,Claudio Viscoli,T. J. Walsh,M. White,J. R. Graybill +22 more
TL;DR: Because of the rapidly increasing incidence of serious candidal infections, a consensus conference of 22 investigators from the United States, Europe, and Japan was held to discuss strategies for the prevention and treatment of deep-organ infections caused by Candida species.
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An EORTC International Multicenter Randomized Trial (EORTC Number 19923) Comparing Two Dosages of Liposomal Amphotericin B for Treatment of Invasive Aspergillosis
M. Ellis,David Spence,B.E. de Pauw,Françoise Meunier,A. Marinus,Laurence Collette,Richard Sylvester,Jacques F. Meis,Marc Boogaerts,Dominik Selleslag,Vladimir Krcmery,W. von Sinner,P. MacDonald,Chantal Doyen,Bernard Vandercam +14 more
TL;DR: This is the first completed prospective randomized clinical efficacy trial of antifungals in the treatment of invasive aspergillosis (IA) and the first to compare the clinical efficacy of two dosages of liposomal amphotericin B (L-AmB) for IA in neutropenic patients with cancer or those undergoing bone marrow transplantation.
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Mucosal barrier injury: biology, pathology, clinical counterparts and consequences of intensive treatment for haematological malignancy: an overview.
TL;DR: The pathobiology, clinical counterparts and the means of measuring MBI are discussed together with potential approaches for prevention, amelioration and, perhaps, even cure.