B
B. Kreymann
Researcher at Hammersmith Hospital
Publications - 8
Citations - 2371
B. Kreymann is an academic researcher from Hammersmith Hospital. The author has contributed to research in topics: Glucagon-like peptide-1 & Glucagon. The author has an hindex of 7, co-authored 8 publications receiving 2299 citations.
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Journal ArticleDOI
Glucagon-like peptide-1 7-36: a physiological incretin in man.
TL;DR: The observation of greatly increased postprandial plasma GLP-1 7-36 levels in patients with postgastrectomy dumping syndrome suggests that it may mediate the hyperinsulinaemia and reactive hypoglycaemia of this disorder.
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Identification and characterization of glucagon-like peptide-1 7–36 amide-binding sites in the rat brain and lung
TL;DR: High‐affinity binding sites for glucagon‐like peptide‐1 7–36 amide (GLP‐17–36 NH2) were identified in rat brain and lung membranes and specific binding in the central nervous system was particularly high in the hypothalamus and the brain stem.
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Glucagon-like peptide-1 (7-36)-NH2 : a physiological inhibitor of gastric acid secretion in man
TL;DR: A novel role is suggested for GLP-1 (7-36)-NH2 as a physiological inhibitor of gastric acid secretion in man after the ingestion of a fat or mixed-component meal.
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Characterization of glucagon-like peptide-1-(7–36)amide in the hypothalamus
B. Kreymann,M. A. Ghatei,Philip W.J. Burnet,Gareth Williams,S.M. Kanse,Arthur R. Diani,Stephen R. Bloom +6 more
TL;DR: GLP-1-(7-36)NH2 appears to fulfil two criteria for a neurotransmitter, no change was found in its hypothalamic content in streptozocin-induced diabetic rats compared to normal controls but a decrease was seen in hyperinsulinemic hyperglycemic KKAy mice compared to KK mice.
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Isolation and characterisation of GLP-1 7-36 amide from rat intestine. Elevated levels in diabetic rats.
TL;DR: Evidence that amidation occurs at an arginine residue during the post‐translational processing of GLP‐1 is provided, providing evidence that amidations occur at anArginine residues duringThe distribution of GLp‐1 7–36 NH2‐like immunoreactivity was determined in the rat gastrointestinal tract.