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Baiming Huang
Researcher at Peking Union Medical College
Publications - 5
Citations - 76
Baiming Huang is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Transcriptome & Immunology. The author has an hindex of 1, co-authored 2 publications receiving 14 citations.
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Journal ArticleDOI
Decoding Human Megakaryocyte Development.
Hongtao Wang,Jian He,Changlu Xu,Xiaoyuan Chen,Hua Yang,Shujuan Shi,Cuicui Liu,Yang Zeng,Dan Wu,Zhijie Bai,Mengge Wang,Yuqi Wen,Pei Su,Meijuan Xia,Baiming Huang,Chunyu Ma,Lihong Bian,Yu Lan,Tao Cheng,Lihong Shi,Bing Liu,Jiaxi Zhou +21 more
TL;DR: Single-cell RNA sequencing of human MKs from embryonic yolk sac and fetal liver is used to characterize the transcriptome, cellular heterogeneity, and developmental trajectories of early megakaryopoiesis and identifies a subpopulation of CD42b+CD14+ MKs in vivo that exhibit high expression of genes associated with immune responses.
Journal ArticleDOI
The heterogeneity of megakaryocytes and platelets and implications for ex vivo platelet generation.
TL;DR: The functional and developmental heterogeneity of megakaryocytes (MKs) and its potential link to the heterogeneity of platelets has been studied in this article, and the implications of these findings while focusing on the ex vivo generation of platelet from human pluripotent stem cells.
Journal ArticleDOI
[Establishment of a platelet production model by bone marrow cavity transplantation of mouse primary megakaryocytes].
TL;DR: An in vivo platelets-producing model of primary megakaryocytes is established using magnetic-bead enrichment and intramedullary injection, which objectively reflects the platelet-producing capacity of megakARYocytes in the bone marrow.
Journal ArticleDOI
Multi-dimensional Dissection of Blood Components reveals an Uncanonical Immune Landscape in SARS-CoV-2 Omicron Patients
Hong Wang,Cuicui Liu,Xiaowei S. Xie,Yingrui Wang,Xuelian Cheng,Mengyao Liu,Rui Sun,Shihui Ma,Huijun Wang,Guo-Qing Zhu,Yang Lu,Baiming Huang,Pei Su,Xiaoyuan Chen,Jingjing Zhao,Hongtao Wang,Lixia Fu,Q L Huang,Yang Yang,He Wang,Chunlong Wu,Weigang Ge,Chen Chen,Qianyu Huo,Qingping Wang,Ying Wang,Liangquan Geng,Yan-Ying Xie,Yingying Xie,Jianwei Qi,Huaiyong Chen,Junping Wu,E. Jiang,Ximo Wang,Zhong-yang Shen,Tiannan Guo,Jiaxi Zhou,Ping Zhu,Tao Cheng +38 more
TL;DR: In this article , the authors dissected the host response dynamics during multiple disease phases to reveal the molecular and cellular landscapes in the blood, and developed a machine learning model that accurately predicted the probability of re-positivity in Omicron patients.
Journal ArticleDOI
Multi-omics blood atlas reveals unique features of immune and platelet responses to SARS-CoV-2 Omicron breakthrough infection
H. Wang,Cuicui Liu,Xiaowei S. Xie,Yingrui Wang,Xuelian Cheng,Biao Zhang,Mengyao Liu,Rui Sun,Shihui Ma,Huijun Wang,Guo-Qing Zhu,Yang Lu,Baiming Huang,Pei Su,Xiaoyuan Chen,Jingjing Zhao,Hongtao Wang,Lixia Fu,Q L Huang,Yang Yang,He Wang,Chunlong Wu,Weigang Ge,Chen Chen,Qianyu Huo,Qingping Wang,Ying Wang,Liangquan Geng,Yan-Ying Xie,Yi Xie,Jianwei Qi,Huaiyong Chen,Junping Wu,E. Jiang,Wen-tao Jiang,Ximo Wang,Zhong-yang Shen,Tiannan Guo,Jiaxi Zhou,Ping Zhu,Tao Cheng +40 more
TL;DR: In this article , the authors dissected the host response dynamics during multiple disease phases to reveal the molecular and cellular landscapes in the blood, and developed a machine learning model that accurately predicted the probability of re-positivity in Omicron patients.