Author
Bao-Ning Su
Bio: Bao-Ning Su is an academic researcher from Lanzhou University. The author has contributed to research in topics: Glycoside & Iridoid. The author has an hindex of 2, co-authored 2 publications receiving 40 citations.
Topics: Glycoside, Iridoid, Aucubin, Verbascoside, Iridoid Glycosides
Papers
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TL;DR: Two new neolignan glycosides were isolated from an ethanolic extract of whole plants of Pedicularis verticillata, along with the known compounds, verbascoside, cistanosides C and D, and were determined to be rel- (7 S ,8 S )-Δ 7′ -9,9′-dihydroxy-3,5′-dimethoxy-7- O -3′,8- O-4
24 citations
TL;DR: A nor-lignan and two sesquiterpenes have been isolated from the medicinal plant Cremanthodium ellisii and their structures were determined on the basis of spectral evidence, especially 2D NMR (1H-1H COSY, HMQC, HMBC).
21 citations
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TL;DR: The recognition that novel units can incorporate into lignins portends significantly expanded opportunities for engineering the composition and consequent properties of lignin for improved utilization of valuable plant resources.
230 citations
TL;DR: Although iridoids exhibit a wide range of pharmacological activities such as cardiovascular, hepatoprotection, hypoglycaemic, antimutagenic, antispasmodic, anti-tumour, antiviral, immunomodulation and purgative effects this review will acutely focus on their anti-inflammatory properties.
Abstract: Inflammation is a manifestation of a wide range of disorders which include; arthritis, atherosclerosis, Alzheimer’s disease, inflammatory bowel syndrome, physical injury and infection amongst many others. Common treatment modalities are usually non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, paracetamol, indomethacin and ibuprofen as well as corticosteroids such as prednisone. These however, may be associated with a host of side effects due to non-selectivity for cyclooxygenase (COX) enzymes involved in inflammation and those with selectivity may be highly priced. Thus, there is a continuing search for safe and effective anti-inflammatory molecules from natural sources. Research has confirmed that iridoids exhibit promising anti-inflammatory activity which may be beneficial in the treatment of inflammation. Iridoids are secondary metabolites present in various plants, especially in species belonging to the Apocynaceae, Lamiaceae, Loganiaceae, Rubiaceae, Scrophulariaceae and Verbenaceae families. Many of these ethnobotanicals have an illustrious history of traditional use alluding to their use to treat inflammation. Although iridoids exhibit a wide range of pharmacological activities such as cardiovascular, hepatoprotection, hypoglycaemic, antimutagenic, antispasmodic, anti-tumour, antiviral, immunomodulation and purgative effects this review will acutely focus on their anti-inflammatory properties. The paper aims to present a summary for the most prominent iridoid-containing plants for which anti-inflammatory activity has been demonstrated in vitro and / or in vivo.
147 citations
TL;DR: In this paper, 5-hydroxyconiferyl alcohol was incorporated into the monomer supply and confirmed that phenols other than the three traditional monolignols can be integrated into plant lignins.
Abstract: Benzodioxane structures are produced in lignins of transgenic poplar plants deficient in COMT, anO-methyltransferase required to produce lignin syringyl units. They result from incorporation of 5-hydroxyconiferyl alcohol into the monomer supply and confirm that phenols other than the three traditional monolignols can be integrated into plant lignins.
105 citations
TL;DR: This review paper aims to provide the researchers with a comprehensive profile of geniposide on its phytochemistry, pharmacology, pharmacokinetics and toxicology in order to highlight some present issues and future perspectives as well as to help develop and utilize this iridoid glycoside more efficiently and safely.
Abstract: Iridoid glycosides are natural products occurring widely in many herbal plants. Geniposide (C17H24O10) is a well-known one, present in nearly 40 species belonging to various families, especially the Rubiaceae. Along with this herbal component, dozens of its natural derivatives have also been isolated and characterized by researchers. Furthermore, a large body of pharmacological evidence has proved the various biological activities of geniposide, such as anti-inflammatory, anti-oxidative, anti-diabetic, neuroprotective, hepatoprotective, cholagogic effects and so on. However, there have been some research articles on its toxicity in recent years. Therefore, this review paper aims to provide the researchers with a comprehensive profile of geniposide on its phytochemistry, pharmacology, pharmacokinetics and toxicology in order to highlight some present issues and future perspectives as well as to help us develop and utilize this iridoid glycoside more efficiently and safely.
90 citations