Baptiste Depalle

TL;DR: It is suggested that both cross-link density and type dictate the stiffness of large deformation regime by increasing the number of interconnected molecules while cross-links mechanical properties determine the failure strain and strength of the fibril.

TL;DR: Collagen hybridizing peptide (CHP), which binds unfolded collagen by triple helix formation, is utilized to detect molecular level subfailure damage to collagen in mechanically stretched rat tail tendon fascicle to elucidate a probable molecular failure mechanism associated with sub failure injuries, and demonstrate the potential of CHP targeting for diagnosis, treatment and monitoring of tissue disease and injury.

TL;DR: In this article, the authors utilize collagen hybridizing peptide (CHP) to detect molecular level sub-failure damage to collagen in mechanically stretched rat tail tendon fascicle.

TL;DR: It is inferred that long‐term ALN treatment compromises micromechanical properties of the bone matrix as assessed ex vivo, and strength deficits are in part related to difference in crystallinity, irrespective of the mineral amount and mineral maturity.

TL;DR: It was showed that elastic deformation was only explained by DMB whereas plasticDeformation was more correlated with collagen maturity, and contact hardness, reflecting both elastic and plastic behaviors, was correlated with both DMB and collagen maturity.