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Barbara A. Wasowska
Researcher at Johns Hopkins University
Publications - 44
Citations - 2229
Barbara A. Wasowska is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Transplantation & Complement system. The author has an hindex of 22, co-authored 40 publications receiving 2161 citations. Previous affiliations of Barbara A. Wasowska include Beth Israel Deaconess Medical Center & Duke University.
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Journal ArticleDOI
Banff '09 meeting report: Antibody mediated graft deterioration and implementation of Banff working groups
Banu Sis,Michael Mengel,Mark Haas,Robert B. Colvin,Philip F. Halloran,Lorraine C. Racusen,Kim Solez,William M. Baldwin,Erika Bracamonte,V. Broecker,Fernando G. Cosio,Anthony J. Demetris,Cinthia B. Drachenberg,Gunilla Einecke,James M. Gloor,Denis Glotz,Edward S. Kraus,Christophe Legendre,Helen Liapis,Roslyn B. Mannon,Brian J. Nankivell,Volker Nickeleit,John C. Papadimitriou,Parmjeet Randhawa,Heinz Regele,Karine Renaudin,E. R. Rodriguez,Daniel Serón,Surya V. Seshan,Manikkam Suthanthiran,Barbara A. Wasowska,Andrea A. Zachary,A. Zeevi +32 more
TL;DR: The willingness of the Banff process to adapt continuously in response to new research and improve potential weaknesses, led to the implementation of six working groups on the following areas: isolated v‐lesion, fibrosis scoring, glomerular lesions, molecular pathology, polyomavirus nephropathy and quality assurance.
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Cytokines, adhesion molecules, and the pathogenesis of chronic rejection of rat renal allografts.
Wayne W. Hancock,Whitley Wd,Stefan G. Tullius,Uwe Heemann,Barbara A. Wasowska,William M. Baldwin,Nicholas L. Tilney +6 more
TL;DR: It is concluded that cytokine production and upregulation of adhesion molecules occurring as part of a cellular immune response may be as important, to the etiology of chronic rejection as the hitherto widely emphasized antibody-mediated host responses.
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Antibody to human leukocyte antigen triggers endothelial exocytosis
Munekazu Yamakuchi,Nancy C. Kirkiles-Smith,Marcella Ferlito,Scott J. Cameron,Clare Bao,Karen Fox-Talbot,Barbara A. Wasowska,William M. Baldwin,Jordan S. Pober,Charles J. Lowenstein +9 more
TL;DR: The data show that antibody to host antigens can activate human endothelial cell exocytosis and leukocyte trafficking, and by triggering vascular inflammation, antibody activation of exocyTosis may play a role in transplant rejection.
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Passive transfer of alloantibodies restores acute cardiac rejection in IgKO mice.
Barbara A. Wasowska,Zhiping Qian,D. Cangello,E Behrens,Khanh Van Tran,Jodi Layton,Fred Sanfilippo,William M. Baldwin +7 more
TL;DR: A model of alloantibody-mediated graft injury is established using B10.A hearts transplanted to wild type or immunoglobulin knock out (IgKO) mice, indicating that macrophage- and T-cell-dependent immune responses were intact in IgKO recipients.
Journal ArticleDOI
Non-complement- and complement-activating antibodies synergize to cause rejection of cardiac allografts.
Salma Rahimi,Zhiping Qian,Jodi Layton,Karen Fox-Talbot,William M. Baldwin,Barbara A. Wasowska +5 more
TL;DR: Non‐complement‐activating AlloAbs stimulate endothelial cells to produce chemokines and this effect is augmented in the milieu of proinflammatory cytokines, indicating that non-complement •activating •AlloAbs can augment injury to allografts by complement‐activated Allo Abs.