B
Barbara Jenkins
Researcher at Harvard University
Publications - 3
Citations - 7456
Barbara Jenkins is an academic researcher from Harvard University. The author has contributed to research in topics: Genetic linkage & Gene. The author has an hindex of 3, co-authored 3 publications receiving 6985 citations.
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Journal ArticleDOI
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
Marcy E. MacDonald,Christine Ambrose,Mabel P. Duyao,Richard H. Myers,Carol Lin,Lakshmi Srinidhi,Glenn Barnes,Sherryl A.M. Taylor,Marianne James,Nicolet Groot,Heather MacFarlane,Barbara Jenkins,Mary Anne Anderson,Nancy S. Wexler,James F. Gusella,Gillian P. Bates,Sarah Baxendale,Holger Hummerich,Susan F. Kirby,Mike North,S. Youngman,Richard Mott,Günther Zehetner,Zdenek Sedlacek,Annemarie Poustka,Anna-Maria Frischauf,Hans Lehrach,Alan Buckler,Deanna M. Church,Lynn Doucette-Stamm,Michael Conlon O'Donovan,Laura Riba-Ramirez,Manish A. Shah,Vincent P. Stanton,Scott A. Strobel,Karen M. Draths,Jennifer L. Wales,Peter B. Dervan,David E. Housman,Michael R. Altherr,Rita Shiang,Leslie M. Thompson,Thomas J. Fielder,John J. Wasmuth,Danilo A. Tagle,John Valdes,Lawrence W. Elmer,Marc W. Allard,Lucio H. Castilla,Manju Swaroop,Kris Blanchard,Francis S. Collins,Russell G. Snell,Tracey Holloway,Kathleen Gillespie,Nicole A. Datson,Duncan Shaw,Peter S. Harper +57 more
TL;DR: In this article, the authors used haplotype analysis of linkage disequilibrium to spotlight a small segment of 4p16.3 as the likely location of the defect, which is expanded and unstable on HD chromosomes.
Journal Article
Assessment of amyloid β-protein precursor gene mutations in a large set of familial and sporadic Alzheimer disease cases
Rudolph E. Tanzi,G Vaula,Donna M. Romano,M Mortilla,Tao Huang,R G Tupler,Wilma Wasco,Bradley T. Hyman,Jonathan L. Haines,Barbara Jenkins +9 more
TL;DR: No APP gene mutations were found in any of the FAD families or sporadic-AD samples examined in this study, suggesting that the mutations in exons 16 and 17 are a rare cause of FAD.
Journal ArticleDOI
Genetic heterogeneity of gene defects responsible for familial Alzheimer disease
Rudolph E. Tanzi,Sandra M. Gaston,Ashley I. Bush,Donna M. Romano,Warren H. Pettingell,Jeffrey Peppercorn,Marc d. Paradis,Sarada Gurubhagavatula,Barbara Jenkins,Wilma Wasco +9 more
TL;DR: This review provides a historical perspective of the search for FAD gene defects and summarizes the progress made in world-wide attempts to isolate and characterize the genes responsible for this disorder.