B
Barbara L. Trommer
Researcher at Northwestern University
Publications - 41
Citations - 7494
Barbara L. Trommer is an academic researcher from Northwestern University. The author has contributed to research in topics: Dentate gyrus & Long-term potentiation. The author has an hindex of 29, co-authored 41 publications receiving 7140 citations. Previous affiliations of Barbara L. Trommer include Maimonides Medical Center & NorthShore University HealthSystem.
Papers
More filters
Journal ArticleDOI
Diffusible, nonfibrillar ligands derived from Aβ1–42 are potent central nervous system neurotoxins
Mary P. Lambert,A. K. Barlow,Brett A. Chromy,C. Edwards,R. Freed,M. Liosatos,Todd E. Morgan,Irina Rozovsky,Barbara L. Trommer,Kirsten L. Viola,Pat Wals,Chuan Zhang,Caleb E. Finch,Grant A. Krafft,William L. Klein +14 more
TL;DR: It is hypothesized that impaired synaptic plasticity and associated memory dysfunction during early stage Alzheimer's disease and severe cellular degeneration and dementia during end stage could be caused by the biphasic impact of Abeta-derived diffusible ligands acting upon particular neural signal transduction pathways.
Journal ArticleDOI
Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
Hai Wei Wang,Joseph F. Pasternak,Joseph F. Pasternak,Helen Kuo,Helen Ristic,Mary P. Lambert,Brett A. Chromy,Kirsten L. Viola,William L. Klein,W. Blaine Stine,Grant A. Krafft,Barbara L. Trommer,Barbara L. Trommer +12 more
TL;DR: The data suggest that soluble non-fibrillar amyloid may contribute to the pathogenesis of AD both by impairing LTP/memory formation at the cellular level and by creating 'neuroplasticity imbalance' manifested by unopposed LTD in the setting of impaired capacity for neural repair via reversal of LTD or LTP.
Journal ArticleDOI
Neural development of selective attention and response inhibition.
James R. Booth,Douglas D. Burman,Joel R. Meyer,Zhang Lei,Barbara L. Trommer,Nicholas D. Davenport,Wei Li,Todd B. Parrish,Darren R. Gitelman,M.-Marsel Mesulam +9 more
TL;DR: Brain activation differences between 12 children and adults examined on two cognitive tasks during functional magnetic resonance imaging (fMRI) are consistent with the prolonged maturation of the fronto-striatal network.
Journal ArticleDOI
Larger deficits in brain networks for response inhibition than for visual selective attention in attention deficit hyperactivity disorder (ADHD).
James R. Booth,James R. Booth,Douglas D. Burman,Joel R. Meyer,Zhang Lei,Barbara L. Trommer,Nicholas D. Davenport,Wei Li,Todd B. Parrish,Darren R. Gitelman,M.-Marsel Mesulam +10 more
TL;DR: The widespread hypoactivity for the ADHD children on the go/no-go task is consistent with the hypothesis that response inhibition is a specific deficit in attention deficit hyperactivity disorder.
Journal ArticleDOI
Cerebral vasospasm and eclampsia.
TL;DR: A patient who experienced focal cerebral and brainstem ischemia in the setting of postpartum eclampsia showed spasm of large- and medium-caliber arteries, which suggests that in such patients cerebral angiography may be informative and useful.