Bayard T. Storey

TL;DR: The results suggest that superoxide dismutase plays the major role in protecting human spermatozoa against lipid peroxidation, and the superoxide Dismutase activity of a fresh sperm sample appears to be a good predictor of the lifetime (up to the complete loss of motility) of that particular sample, and so may prove useful in semen analysis.

TL;DR: A mechanism for spontaneous lipid peroxidation in mammalian sperm is postulated which involves reaction of lipid hydroperoxide and O2 as the rate-determining step and the key intermediate is lipid hydro peroxide generated by a chain reaction initiated by and utilizing superoxide.

TL;DR: Intact human sperm incorporated radiolabelled fatty acids into membrane phospholipids when incubated in medium containing bovine serum albumin as a fatty acid carrier, indicating that aospholipase A2 may act in peroxidative defense by excising a hydroperoxy acyl group from phospholIPid and providing the hydro peroxy fatty acid product as substrate to glutathione peroxIDase.

TL;DR: The results imply that spermatozoa showing CTC fluorescence pattern B can be considered to be capacitated and that a functional definition for capacitation is the acquired ability to undergo the acrosome reaction rapidly when treated with acid-solubilized zonae pellucidae.

TL;DR: These inhibitors make it possible to isolate the two respiratory pathways and study their mode of action separately, and enhance an electron paramagnetic resonance signal near g = 2 in anaerobic, submitochondrial particles from skunk cabbage, which appears to be specific to the alternate oxidase and thus provides a means for its assay.