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Beat Müllhaupt
Researcher at University of Zurich
Publications - 289
Citations - 17086
Beat Müllhaupt is an academic researcher from University of Zurich. The author has contributed to research in topics: Hepatitis C & Liver transplantation. The author has an hindex of 55, co-authored 258 publications receiving 14656 citations.
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Journal ArticleDOI
Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study
Sarah Blach,Stefan Zeuzem,Michael Manns,Ibrahim Altraif,Ann-Sofi Duberg,David H. Muljono,Imam Waked,Seyed M Alavian,Mei Hsuan Lee,Francesco Negro,Faisal Abaalkhail,Ahmed Abdou,Maheeba Abdulla,Antoine Abou Rached,Inka Aho,Ulus Salih Akarca,Imad Al Ghazzawi,Saad Al Kaabi,Faryal Al Lawati,Khalid Al Namaani,Youssif Al Serkal,Said A. Al-Busafi,Layla Al-Dabal,Soo Aleman,Abdullah S. Alghamdi,Abdulrahman Aljumah,Hamad Al-Romaihi,Monique Andersson,Vic Arendt,Perttu Arkkila,Abdullah M. Assiri,Oidov Baatarkhuu,Abate Bane,Ziv Ben-Ari,Colm Bergin,Fernando Bessone,Florian Bihl,Abdul Rahman Bizri,M. Blachier,Antonio Javier Blasco,Carlos E Brandão Mello,Philip Bruggmann,Cheryl Brunton,Filipe Calinas,Henry Lik-Yuen Chan,Asad Chaudhry,Hugo Cheinquer,Chien-Jen Chen,Rong-Nan Chien,Moon Seok Choi,Peer Brehm Christensen,Wan-Long Chuang,Vladimir Chulanov,Laura Cisneros,Mette Rye Clausen,Matthew E. Cramp,Antonio Craxì,E. A. Croes,Olav Dalgard,Jorge Daruich,Victor de Ledinghen,Gregory J. Dore,Manal H El-Sayed,Gül Ergör,Gamal Esmat,Chris Estes,Karolin Falconer,Elmoubashar Farag,Maria Lucia Gomes Ferraz,Paulo R. Ferreira,Robert Flisiak,Sona Frankova,Ivane Gamkrelidze,Edward Gane,Javier García-Samaniego,Akram Khan,Ilias Gountas,Adrian Goldis,Magnus Gottfredsson,Jason Grebely,Michael Gschwantler,Mario G. Pessoa,Jessie Gunter,Behzad Hajarizadeh,Omer Hajelssedig,Saeed Hamid,Waseem Hamoudi,Angelos Hatzakis,Sayed Himatt,Harald Hofer,Irena Hrstić,Yee Tak Hui,Béla Hunyady,Ramazan Idilman,Wasim Jafri,Rohani Jahis,Naveed Z. Janjua,Peter Jarcuska,Agita Jeruma,Jon G. Jonasson,Yasser Kamel,Jia-Horng Kao,Sabahattin Kaymakoglu,David Kershenobich,Jawad Khamis,Young Sik Kim,Loreta A. Kondili,Zaher Koutoubi,Mel Krajden,Henrik Krarup,Moon sing Lai,Wim Laleman,Wai-cheung C Lao,Daniel Lavanchy,Pablo Lázaro,Henri Leleu,Olufunmilayo A. Lesi,Laurentius A. Lesmana,Michael Li,Valentina Liakina,Young-Suk Lim,Boris Lukšić,Adam Mahomed,Matti Maimets,Mihály Makara,Abraham O. Malu,Rui Tato Marinho,Paul Marotta,Stefan Mauss,Muhammad S. Memon,Maria C Mendes Correa,Nahum Méndez-Sánchez,Shahin Merat,Ammal M. Metwally,Rosmawati Mohamed,Christophe Moreno,Fadi H. Mourad,Beat Müllhaupt,Kimberly Murphy,Helen Nde,Richard Njouom,Diana Nonković,Suzanne Norris,Solomon Obekpa,Stephen Oguche,S. Olafsson,Marian Oltman,Ogu Omede,CE Omuemu,Ohene Opare-Sem,Anne Øvrehus,Shirley Owusu-Ofori,Tsendsuren S. Oyunsuren,George V. Papatheodoridis,Ken Pasini,Kevork M. Peltekian,Richard Phillips,N. N. Pimenov,Hossein Poustchi,Nishi Prabdial-Sing,Huma Qureshi,Alnoor Ramji,Devin Razavi-Shearer,Kathryn Razavi-Shearer,Berhane Redae,Henk W. Reesink,Ezequiel Ridruejo,Sarah Robbins,Lewis R. Roberts,Stuart K. Roberts,William Rosenberg,Françoise Roudot-Thoraval,Stephen D. Ryder,Rifaat Safadi,Olga Sagalova,Riina Salupere,Faisal M. Sanai,Juan F.Sanchez Avila,Vivek A. Saraswat,Rui Sarmento-Castro,Christoph Sarrazin,Jonathan Schmelzer,Ivan Schréter,Carole Seguin-Devaux,Samir Shah,Ala I. Sharara,Manik Sharma,Anatoly Shevaldin,Gamal Shiha,William Sievert,Mark W. Sonderup,Kyriakos Souliotis,Danute Speiciene,Jan Sperl,Peter Stärkel,Rudolf E. Stauber,Catherine A.M. Stedman,Daniel Struck,Tung-Hung Su,Vana Sypsa,Soek Siam Tan,Junko Tanaka,Alexander J. Thompson,Ieva Tolmane,Krzysztof Tomasiewicz,Jonas Valantinas,Pierre Van Damme,Adriaan J. van der Meer,Ingo van Thiel,Hans Van Vlierberghe,Adriana Vince,Wolfgang Vogel,Heiner Wedemeyer,Nina Weis,Vincent Ws Wong,Cesar Yaghi,Ayman Yosry,Man-Fung Yuen,Evy Yunihastuti,Aasim Yusuf,Eli Zuckerman,Homie Razavi +221 more
TL;DR: The global estimate of viraemic HCV infections is lower than previous estimates, largely due to more recent prevalence estimates in Africa, and increased mortality due to liver-related causes and an ageing population may have contributed to a reduction in infections.
Journal ArticleDOI
Telaprevir for retreatment of HCV infection.
Stefan Zeuzem,Pietro Andreone,Stanislas Pol,Eric Lawitz,Moisés Diago,Stuart K. Roberts,R. Focaccia,Zobair M. Younossi,Graham R. Foster,Andrzej Horban,Peter Ferenci,Frederik Nevens,Beat Müllhaupt,Paul J. Pockros,R. Terg,Daniel Shouval,Bart van Hoek,Ola Weiland,Rolf van Heeswijk,Sandra De Meyer,Don Luo,G. Boogaerts,Ramon Polo,Gaston Picchio,Maria Beumont +24 more
TL;DR: Telaprevir combined with peginterferon plus ribavirin significantly improved rates of sustained virologic response in patients with previously treated HCV infection, regardless of whether there was a lead-in phase.
Journal ArticleDOI
Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study
Andri Rauch,Zoltán Kutalik,Zoltán Kutalik,Patrick Descombes,Tao Cai,Julia di Iulio,Tobias Mueller,Murielle Bochud,Manuel Battegay,Enos Bernasconi,Jan Borovicka,Sara Colombo,Andreas Cerny,Jean-François Dufour,Hansjakob Furrer,Huldrych F. Günthard,Markus H. Heim,Bernard Hirschel,Raffaele Malinverni,Darius Moradpour,Beat Müllhaupt,Andrea Witteck,Jacques S. Beckmann,Jacques S. Beckmann,Thomas Berg,Sven Bergmann,Sven Bergmann,Francesco Negro,Amalio Telenti,Pierre-Yves Bochud +29 more
TL;DR: The association of the IL28B locus with natural and treatment-associated control of HCV indicates the importance of innate immunity and interferon lambda in the pathogenesis ofHCV infection.
Journal ArticleDOI
Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study
Devin Razavi-Shearer,Ivane Gamkrelidze,Mindie H. Nguyen,Ding-Shinn Chen,Pierre Van Damme,Zaigham Abbas,Maheeba Abdulla,Antoine Abou Rached,Danjuma Adda,Inka Aho,Ulus Salih Akarca,Fuad Hasan,Faryal Al Lawati,Khalid Al Naamani,Hamad I. Al-Ashgar,Seyed M Alavian,Sameer Alawadhi,Agustín Albillos,Said A. Al-Busafi,Soo Aleman,Faleh Z. Al-Faleh,Abdulrahman Aljumah,Anil C. Anand,Nguyen Thu Anh,Joop E. Arends,Perttu Arkkila,Kostas Athanasakis,Abate Bane,Ziv Ben-Ari,Thomas Berg,Abdul Rahman Bizri,Sarah Blach,Carlos E Brandão Mello,Samantha M Brandon,Bisi Bright,Philip Bruggmann,Maurizia Rossana Brunetto,Maria Buti,Henry Lik-Yuen Chan,Asad Chaudhry,Rong-Nan Chien,Moon Seok Choi,Peer Brehm Christensen,Wan-Long Chuang,Vladimir Chulanov,Mette Rye Clausen,Massimo Colombo,Markus Cornberg,Benjamin C Cowie,Antonio Craxì,E. A. Croes,Diego Alberto Cuellar,Chris Cunningham,Hailemichael Desalegn,Sylvia Drazilova,Ann-Sofi Duberg,Steve S Egeonu,Manal H El-Sayed,Chris Estes,Karolin Falconer,Maria Lucia Gomes Ferraz,Paulo R. Ferreira,Robert Flisiak,Sona Frankova,Giovanni Battista Gaeta,Javier García-Samaniego,Jordan Genov,Jan Gerstoft,Adrian Goldis,Ilias Gountas,Richard Gray,Mario G. Pessoa,Behzad Hajarizadeh,Angelos Hatzakis,Christophe Hézode,Sayed Himatt,Andy I. M. Hoepelman,Irena Hrstić,Yee Tak Hui,Petr Husa,Rohani Jahis,Naveed Z. Janjua,Peter Jarcuska,Jerzy Jaroszewicz,Sabahattin Kaymakoglu,David Kershenobich,Loreta A. Kondili,Aliya Konysbekova,Mel Krajden,Pavol Kristian,Wim Laleman,Wai-cheung C Lao,Jen Layden,Jeffrey V. Lazarus,Mei Hsuan Lee,Valentina Liakina,Young-Suk Lim,Ching-kong K Loo,Boris Lukšić,Reza Malekzadeh,Abraham O. Malu,Adkhamjon Mamatkulov,Michael Manns,Rui Tato Marinho,Mojca Matičič,Stefan Mauss,Muhammad S. Memon,Maria C Mendes Correa,Nahum Méndez-Sánchez,Shahin Merat,Ammal M. Metwally,Rosmawati Mohamed,Jacques E Mokhbat,Christophe Moreno,Joël Mossong,Fadi H. Mourad,Beat Müllhaupt,Kimberly Murphy,Erkin Musabaev,Arif Nawaz,Helen Nde,Francesco Negro,Alexander Nersesov,Van Thi Thuy Nguyen,Richard Njouom,Renovat Ntagirabiri,Zuridin Nurmatov,Solomon Obekpa,Ponsiano Ocama,Stephen Oguche,Ogu Omede,CE Omuemu,Ohene Opare-Sem,Christopher K Opio,Necati Örmeci,George V. Papatheodoridis,Ken Pasini,N. N. Pimenov,Hossein Poustchi,Trân D Quang,Huma Qureshi,Alnoor Ramji,Kathryn Razavi-Shearer,Berhane Redae,Henk W. Reesink,Cielo Yaneth Rios,Gabriela Rjaskova,Sarah Robbins,Lewis R. Roberts,Stuart K. Roberts,Stephen D. Ryder,Rifaat Safadi,Olga Sagalova,Riina Salupere,Faisal M. Sanai,Juan Francisco Sánchez-Ávila,Vivek A. Saraswat,Christoph Sarrazin,Jonathan Schmelzer,Ivan Schréter,Julia A. Scott,Carole Seguin-Devaux,Samir Shah,Ala I. Sharara,Manik Sharma,Gamal Shiha,Tesia Shin,William Sievert,Jan Sperl,Peter Stärkel,Catherine A.M. Stedman,Vana Sypsa,Frank Tacke,Soek Siam Tan,Junko Tanaka,Krzysztof Tomasiewicz,Petr Urbánek,Adriaan J. van der Meer,Hans Van Vlierberghe,Stefano Vella,Adriana Vince,Yasir Waheed,Imam Waked,Nick Walsh,Nina Weis,Vincent Wai-Sun Wong,Joseph Woodring,Cesar Yaghi,Hwai I. Yang,Chung-Lin Yang,Kakharman Yesmembetov,Ayman Yosry,Man-Fung Yuen,Muhammed Aasim M Yusuf,Stefan Zeuzem,Homie Razavi +195 more
TL;DR: The estimate of HBV prevalence in 2016 differs from previous studies, potentially because it took into account the effect of infant prophylaxis and early childhood vaccination, as well as changing prevalence over time.
Journal ArticleDOI
Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial
Rafael Bañares,Rafael Bañares,Frederik Nevens,Fin Stolze Larsen,Rajiv Jalan,Agustín Albillos,Matthias M. Dollinger,Faouzi Saliba,Faouzi Saliba,Tilman Sauerbruch,Sebastian Klammt,Johann Ockenga,Albert Parés,Julia Wendon,Tanja Brünnler,Ludwig Kramer,Philippe Mathurin,Manuel de la Mata,Antonio Gasbarrini,Beat Müllhaupt,Alexander Wilmer,Wim Laleman,Martin Eefsen,Sambit Sen,Alexander Zipprich,Teresa Tenorio,Marco Pavesi,Hartmut Schmidt,Steffen Mitzner,Roger Williams,Vicente Arroyo +30 more
TL;DR: At scheduled doses, a beneficial effect on survival of MARS therapy in patients with ACLF could not be demonstrated, however, MARS has an acceptable safety profile, has significant dialysis effect, and nonsignificantly improves severe HE.