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Béatrice Horard
Researcher at École normale supérieure de Lyon
Publications - 38
Citations - 1787
Béatrice Horard is an academic researcher from École normale supérieure de Lyon. The author has contributed to research in topics: Chromatin & Zygote. The author has an hindex of 19, co-authored 35 publications receiving 1610 citations. Previous affiliations of Béatrice Horard include Lyon College & University of Lyon.
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Journal ArticleDOI
Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand
TL;DR: The purpose of this review is to summarize knowledge of the nature of ERR activities and progresses in identifying synthetic ERR modulators.
Journal ArticleDOI
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect
Erica Salvati,Carlo Leonetti,Angela Maria Rizzo,Marco Scarsella,Marcella Mottolese,Rossella Galati,Isabella Sperduti,Malcolm F. G. Stevens,Maurizio D'Incalci,Maria A. Blasco,Giovanna Chiorino,Serge Bauwens,Béatrice Horard,Eric Gilson,Antonella Stoppacciaro,Gabriella Zupi,Annamaria Biroccio +16 more
TL;DR: It is shown that RHPS4 triggers a rapid and potent DNA damage response at telomeres in human transformed fibroblasts and melanoma cells, and the key role of telomere-protective factors TRF2 and POT1 in response to this anti-telomere strategy is revealed.
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Jumping genes and epigenetics: Towards new species
TL;DR: It is suggested that macroevolution and speciation might originate when the host relaxes its epigenetic control of TEs and the resulting TE mobilization drives genome restructuring that may sometimes provide the host with an innovative genetic escape route.
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Characterization of oestrogen receptors in zebrafish (Danio rerio).
TL;DR: It is concluded that oestrogen signal transduction can operate during zebrafish development only within discrete time windows, as observed by RNase protection assays.
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The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats
Thomas Simonet,Laure-Emmanuelle Zaragosi,Claude Philippe,Kevin Lebrigand,Clémentine Schouteden,Adeline Augereau,Adeline Augereau,Serge Bauwens,Jing Ye,Jing Ye,Marco Santagostino,Elena Giulotto,Frédérique Magdinier,Béatrice Horard,Pascal Barbry,Rainer Waldmann,Eric Gilson,Eric Gilson +17 more
TL;DR: It is proposed that TRF1 and TRF2 couple the functional state of telomeres to the long-range organization of chromosomes and gene regulation networks by binding to extratelomeric sequences.