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Bellur S. Prabhakar
Researcher at University of Illinois at Chicago
Publications - 246
Citations - 10799
Bellur S. Prabhakar is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Antibody & Thyrotropin receptor. The author has an hindex of 55, co-authored 241 publications receiving 9686 citations. Previous affiliations of Bellur S. Prabhakar include National Institutes of Health & University of Texas Medical Branch.
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Current Perspective on the Pathogenesis of Graves’ Disease and Ophthalmopathy
TL;DR: Recent studies related to the molecular mechanisms of the disease pathogenesis and the development of animal models for GD have led to a better understanding of the pathogenesis of GD and GO and have opened up potential new avenues for developing novel treatments.
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A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
Kiira Ratia,Scott D. Pegan,Jun Takayama,Katrina Sleeman,Melissa M. Coughlin,Surendranath Baliji,Rima Chaudhuri,Wentao Fu,Bellur S. Prabhakar,Michael E. Johnson,Susan C. Baker,Arun K. Ghosh,Andrew D. Mesecar +12 more
TL;DR: Findings provide proof-of-principle that PLpro is a viable target for development of antivirals directed against SARS-CoV, and that potent noncovalent cysteine protease inhibitors can be developed with specificity directed toward pathogenic deubiquitinating enzymes without inhibiting host DUBs.
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miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway
TL;DR: The data reveal a novel model in which a miRNA can regulate apoptosis through targeting the mitochondrial fission machinery, and identify that miR-30 family members can suppress p53 expression.
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Molecular mimicry: frequency of reactivity of monoclonal antiviral antibodies with normal tissues.
Javaraiah Srinivasappa,Junzo Saegusa,Bellur S. Prabhakar,M K Gentry,Michael J. Buchmeier,T J Wiktor,Hilary Koprowski,Michael B. A. Oldstone,A. L. Notkins +8 more
TL;DR: It was concluded that the reactivity of monoclonal antiviral antibodies with normal tissues is a common phenomenon.
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Regulatory T cells in multiple sclerosis and myasthenia gravis
TL;DR: Several strategies of treatment which have been shown to be effective or are proposed as potential therapies to restore the function of various Treg subsets including Tr1, iTr35, nTregs, and iTregs appear promising for treating patients with MS or MG.