Ben J. Cohlen

TL;DR: All of the current methods of endometrial preparation appear to be equally successful in terms of ongoing pregnancy rate, however, in some comparisons predominantly retrospective studies were included leaving these comparisons subject to selection and publication bias.

TL;DR: Whether, for couples with unexplained subfertility, IUI improves the live birth rate compared with timed intercourse (TI), or expectant management, both with and without ovarian hyperstimulation (OH), is investigated.

TL;DR: There is insufficient evidence to recommend any specific preparation technique, and large high quality randomised controlled trials, comparing the effectiveness of a gradient and/or a swim-up and/ or wash and centrifugation technique on clinical outcome are lacking.

TL;DR: Robust evidence is lacking but based on the available results gonadotrophins might be the most effective drugs when IUI is combined with ovarian hyperstimulation, and low dose protocols are advised since pregnancy rates do not differ from pregnancy rates which result from high dose regimen, whereas the chances to encounter negative effects from ovarian stimulation such as multiples and OHSS are limited with low dose gonadotropic drugs.

TL;DR: LBRs after AC-Fet were not inferior to those achieved by mNC-FET and the lack of superiority was confirmed, and no significant differences in clinical and OPR were observed.