Benjamin Yakir

TL;DR: A third type of aneuploidy already evident in early passage HiPSCs is revealed, suggesting considerable selective pressure during the reprogramming process, and high incidence of chromosome 12 duplications is indicated, resulting in significant enrichment for cell cycle-related genes.

TL;DR: An efficient approach to gene discovery is reported that found a highly significant association between schizophrenia and a COMT haplotype and can be widely implemented for the genetic dissection of other common diseases.

TL;DR: It is found that LD (in terms of r(2)) decreases as a function of distance even within the so-called 'haplotype blocks', which has significant consequences when using LD mapping for the genetic dissection of complex traits, as higher density SNP maps will be required to scan the genome.

TL;DR: The purpose of this whole-genome association study was to discover novel T2D-associated genes, and the most significant replicated result was found at the AHI1-LOC441171 gene region.

TL;DR: The association between COMT and bipolar disorder was tested by examining the allele and haplotype found to be associated with schizophrenia and a significant association between bipolar disorder and COMT polymorphisms was found.