B
Bernd L. Fiebich
Researcher at University of Freiburg
Publications - 254
Citations - 15748
Bernd L. Fiebich is an academic researcher from University of Freiburg. The author has contributed to research in topics: Receptor & Microglia. The author has an hindex of 58, co-authored 242 publications receiving 14108 citations. Previous affiliations of Bernd L. Fiebich include University Medical Center Freiburg & Symrise.
Papers
More filters
Journal ArticleDOI
Inflammation and Alzheimer's disease.
Haruhiko Akiyama,Steven W. Barger,Scott R. Barnum,B Bradt,Jürgen Bauer,Greg M. Cole,Neil R. Cooper,Piet Eikelenboom,Mark R. Emmerling,Bernd L. Fiebich,Caleb E. Finch,Sally A. Frautschy,W. S. T. Griffin,Harald Hampel,Michael Hüll,Gary E. Landreth,Lih-Fen Lue,Robert E. Mrak,Ian R. A. Mackenzie,Patrick L. McGeer,M K O'Banion,Joel S. Pachter,Giulio Maria Pasinetti,C Plata-Salaman,Joseph G. Rogers,Russell E. Rydel,Yueyang Shen,Wolfgang J. Streit,Ronald Strohmeyer,I Tooyoma,F L van Muiswinkel,R. Veerhuis,David G. Walker,Scott D. Webster,Beatrice Hauss–Wegrzyniak,Gary L. Wenk,Tony Wyss-Coray +36 more
TL;DR: By better understanding AD inflammatory and immunoregulatory processes, it should be possible to develop anti-inflammatory approaches that may not cure AD but will likely help slow the progression or delay the onset of this devastating disorder.
Journal ArticleDOI
Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.
TL;DR: The findings indicate that the proliferation and activation of microglia contributes to excitotoxicity, which is inhibited by minocycline, an antibiotic used in severe human infections.
Journal ArticleDOI
The serotoninergic receptors of human dendritic cells: identification and coupling to cytokine release.
Marco Idzko,Elisabeth Panther,Christian Stratz,Tobias Müller,Hannes Bayer,Gernot Zissel,Thorsten Dürk,Stephan Sorichter,Francesco Di Virgilio,Michael Geissler,Bernd L. Fiebich,Yared Herouy,Peter Elsner,Johannes Norgauer,Davide Ferrari +14 more
TL;DR: The study shows that 5-HT stimulated, in a maturation-dependent manner, different signaling pathways in DC, pointing to a role for 5- HT in regulating the immune response at peripheral sites.
Journal ArticleDOI
Expression and regulation of cyclooxygenase-2 in rat microglia
Manuel K. A. Bauer,Klaus Lieb,Klaus Schulze-Osthoff,Mathias Berger,Peter J. Gebicke-Haerter,Joachim Bauer,Bernd L. Fiebich +6 more
TL;DR: The results suggest that microglia may represent an important source of prostanoids in the brain, thus reinforcing their prominent role in cerebral inflammatory processes.
Journal ArticleDOI
Lipopolysaccharide-Induced Neuroinflammation as a Bridge to Understand Neurodegeneration.
Carla R.A. Batista,Giovanni Freitas Gomes,Eduardo Candelario-Jalil,Bernd L. Fiebich,Antônio Carlos Pinheiro de Oliveira +4 more
TL;DR: The use of LPS in various models of neurodegeneration is reviewed as well as the neuroinflammatory mechanisms induced by this toxin that could underpin the pathological events linked to the Neurodegenerative process are discussed.