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Bernt Krebs

Researcher at University of Münster

Publications -  730
Citations -  16948

Bernt Krebs is an academic researcher from University of Münster. The author has contributed to research in topics: Crystal structure & Ligand. The author has an hindex of 56, co-authored 729 publications receiving 16336 citations. Previous affiliations of Bernt Krebs include Leiden University & Clariant.

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Crystal structure of a plant catechol oxidase containing a dicopper center.

TL;DR: Based on biochemical, spectroscopic and the presented structural data, a catalytical mechanism is proposed in which one of the oxygen atoms of the diphenolic substrate binds to CuB ofThe oxygenated enzyme.
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Two-Metal Ion Catalysis in Enzymatic Acyl- and Phosphoryl-Transfer Reactions

TL;DR: A remarkable diversity is also seen in the structures of the active sites of these di- and trinuclear metalloenzymes, even for enzymes that catalyze very similar reactions, including hydrolytic cleavage of phosphomono-, -di- and -triester bonds, phosphoanhydride bonds as well as of peptide bonds or urea.
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The crystal structure of catechol oxidase : new insight into the function of type-3 copper proteins

TL;DR: Comparison between the 3D structures of catechol oxidase and hemocyanins reveals the structural reasons for the divergence in function.
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Crystal structure of a purple acid phosphatase containing a dinuclear Fe(III)-Zn(II) active site.

TL;DR: The active-site structure of the homodimeric 111-kilodalton KBPAP is consistent with previous proposals regarding the mechanism of phosphate ester hydrolysis involving nucleophilic attack on the phosphate group by an Fe(III)-coordinated hydroxide ion.
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Metallothioneins: zinc, cadmium, mercury, and copper thiolates and selenolates mimicking protein active site features--structural aspects and biological implications.

TL;DR: It is concluded that the long sought role of MT lies in the control of the cellular zinc distribution as a function of the energy state of the cell and not in the widely held belief that MT primarily scavenges radicals or detoxifies metals.