B
Bertrand Lell
Researcher at University of Tübingen
Publications - 14
Citations - 3593
Bertrand Lell is an academic researcher from University of Tübingen. The author has contributed to research in topics: Plasmodium falciparum & Malaria. The author has an hindex of 14, co-authored 14 publications receiving 3376 citations. Previous affiliations of Bertrand Lell include University of Vienna & Albert Schweitzer Hospital.
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Journal ArticleDOI
Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10.
Anita H. J. van den Biggelaar,Ronald van Ree,Laura C. Rodrigues,Bertrand Lell,André M. Deelder,Peter G. Kremsner,Maria Yazdanbakhsh +6 more
TL;DR: The anti-inflammatory cytokine, interleukin-10, induced in chronic schistosomiasis, appears central to suppressing atopy in African children.
Journal ArticleDOI
Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
Selidji T Agnandji,Angela Huttner,Madeleine E Zinser,Patricia Njuguna,Christine Dahlke,José Francisco Fernandes,Sabine Yerly,Julie-Anne Dayer,Verena Kraehling,Rahel Kasonta,A.A. Adegnika,Marcus Altfeld,Floriane Auderset,Emmanuel B. Bache,Nadine Biedenkopf,Saskia Borregaard,Jessica S Brosnahan,Rebekah Burrow,Christophe Combescure,Jules Alexandre Desmeules,Markus Eickmann,Sarah Katharina Fehling,Axel Finckh,Ana Rita Gonçalves,Martin P. Grobusch,Jay W. Hooper,Alen Jambrecina,Anita Lumeka Kabwende,Gürkan Kaya,Domtila Kimani,Bertrand Lell,Barbara Lemaître,Ansgar W. Lohse,Marguerite Massinga-Loembe,Alain Matthey,Benjamin Mordmüller,Anne Nolting,Caroline Ogwang,Michael Ramharter,Jonas Schmidt-Chanasit,Stefan Schmiedel,Peter Silvera,Felix R. Stahl,Henry M. Staines,Thomas Strecker,Hans Stubbe,Benjamin Tsofa,Sherif R. Zaki,Patricia E. Fast,Vasee S. Moorthy,Laurent Kaiser,Sanjeev Krishna,Stephan Becker,Marie-Paule Kieny,Philip Bejon,Peter G. Kremsner,Marylyn M. Addo,Claire-Anne Siegrist +57 more
TL;DR: RVSV-ZEBOV was reactogenic but immunogenic after a single dose and warrants further evaluation for safety and efficacy, and glycoprotein-binding antibody titers were sustained through 180 days in all participants.
Journal ArticleDOI
Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine
Daniel E. Neafsey,Michal Juraska,Trevor Bedford,David Benkeser,Clarissa Valim,Allison D. Griggs,Marc Lievens,Salim Abdulla,Samuel Adjei,Tsiri Agbenyega,Selidji T Agnandji,Pedro Aide,Scott Anderson,Daniel Ansong,John J. Aponte,Kwaku-Poku Asante,Philip Bejon,Ashley J. Birkett,Myriam Bruls,Kristen M Connolly,Umberto D'Alessandro,Carlota Dobaño,Samwel Gesase,Brian Greenwood,Jonna Grimsby,Halidou Tinto,Mary J. Hamel,Irving F. Hoffman,Portia Kamthunzi,Simon Kariuki,Peter G. Kremsner,Amanda J. Leach,Bertrand Lell,Niall Lennon,John Lusingu,Kevin Marsh,Francis Martinson,Jackson T Molel,Eli L. Moss,Patricia Njuguna,Christian F. Ockenhouse,Bernhards Ogutu,Walter Otieno,Lucas Otieno,Kephas Otieno,Seth Owusu-Agyei,Daniel J. Park,Karell G. Pellé,Dana Robbins,Carsten Russ,Elizabeth M. Ryan,Jahit Sacarlal,Brian Sogoloff,Hermann Sorgho,Marcel Tanner,Thor G. Theander,Innocent Valea,Sarah K Volkman,Qing Yu,Didier Lapierre,Bruce W. Birren,Peter B. Gilbert,Dyann F. Wirth +62 more
TL;DR: It is suggested that among children 5 to 17 months of age, the RTS,S vaccine has greater activity against malaria parasites with the matched circumsporozoite protein allele than against mismatched malaria.
Journal ArticleDOI
Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trial.
Martin Adjuik,Patrice Agnamey,Abdel Babiker,Steffen Borrmann,Steffen Borrmann,Philippe Brasseur,M. Cisse,Frank Cobelens,Diallo S,Jean-François Faucher,Paul Garner,S. Gikunda,Peter G. Kremsner,Peter G. Kremsner,Sanjeev Krishna,Sanjeev Krishna,Bertrand Lell,Bertrand Lell,M. Loolpapit,Pierre-Blaise Matsiegui,Michel A. Missinou,Michel A. Missinou,J. Mwanza,Francine Ntoumi,Piero Olliaro,P. Osimbo,Philipp Rezbach,Philipp Rezbach,Eliab Some,Walter R. J. Taylor +29 more
TL;DR: The combination of artesunate and amodiaquine improved treatment efficacy in Gabon and Kenya, and was equivalent in Sénégal, and is a potential combination for use in Africa.
Journal ArticleDOI
Interferon-γ Responses Are Associated with Resistance to Reinfection with Plasmodium falciparum in Young African Children
Adrian J. F. Luty,Bertrand Lell,Ruprecht Schmidt-Ott,Leopold Gustave Lehman,Doris Luckner,Bernhard Greve,Peter Matousek,Klaus Herbich,Daniela Schmid,Florence Migot-Nabias,Philippe Deloron,Ruth S. Nussenzweig,Peter G. Kremsner +12 more
TL;DR: Differences in the Th1/Th2 cytokine balance may be linked to the ability to control parasite multiplication in these young children, helping to explain the marked differences observed in both susceptibility to infection as well as in clinical presentation.