B
Bhavana Prasher
Researcher at Institute of Genomics and Integrative Biology
Publications - 31
Citations - 664
Bhavana Prasher is an academic researcher from Institute of Genomics and Integrative Biology. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 9, co-authored 24 publications receiving 496 citations. Previous affiliations of Bhavana Prasher include Academy of Scientific and Innovative Research & Council of Scientific and Industrial Research.
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Journal ArticleDOI
Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda
Bhavana Prasher,Sapna Negi,Shilpi Aggarwal,A. Mandal,Tav P Sethi,S.R. Deshmukh,Sudha G Purohit,Shantanu Sengupta,Sangeeta Khanna,Farhan Mohammad,Gaurav Garg,Samir K. Brahmachari,Mitali Mukerji +12 more
TL;DR: This study makes a first attempt towards unraveling the clinical phenotyping principle of a traditional system of medicine in terms of modern biology using Ayurveda based method of phenotypic classification of extreme constitutional types.
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EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda
Shilpi Aggarwal,Sapna Negi,Pankaj Jha,Prashant Singh,Tsering Stobdan,M. A. Qadar Pasha,Saurabh Ghosh,Anurag Agrawal,Bhavana Prasher,Mitali Mukerji +9 more
TL;DR: A link between high-altitude adaptation and common variations rs479200 (C/T) and rs480902 (T/C) in the EGLN1 gene is reported, and a genotype rare in highlanders but overrepresented in a subgroup of normal lowlanders discernable by Ayurveda may confer increased risk for high-ALTitude pulmonary edema.
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Western Indian Rural Gut Microbial Diversity in Extreme Prakriti Endo-Phenotypes Reveals Signature Microbes
Nar Singh Chauhan,Rajesh Pandey,Anupam Kumar Mondal,Shashank Gupta,Manoj Kumar Verma,Sweta Jain,Vasim Ahmed,Rutuja Patil,Dhiraj Agarwal,Bhushan Girase,Ankita Shrivastava,Fauzul Mobeen,Vikas Sharma,Tulika P. Srivastava,Sanjay Juvekar,Bhavana Prasher,Mitali Mukerji,Debasis Dash +17 more
TL;DR: This study reveals that despite overall uniform composition of gut microbial community, healthy individuals belonging to different Prakriti groups have enrichment of specific bacteria, highlighting the importance of Prakitti based endo-phenotypes to explain the variability amongst healthy individuals in gut microbial flora.
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Genomic insights into ayurvedic and western approaches to personalized medicine
TL;DR: It is illustrated how a unique integrative ‘Ayurgenomics’ approach can be used to integrate the trisutra concept of Ayurveda with genomics, and how EGLN1 could qualify as a molecular equivalent of tridosha that can modulate different phenotypic outcomes.
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Ayurgenomics: a new way of threading molecular variability for stratified medicine.
TL;DR: An enormous amount of variability in human genomes could contribute to adaptation, phenotypic variability, disease susceptibility, and response to environment even within healthy individuals of a population.