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Bhavik Anil Patel
Researcher at University of Brighton
Publications - 130
Citations - 2962
Bhavik Anil Patel is an academic researcher from University of Brighton. The author has contributed to research in topics: Serotonin & Nitric oxide synthase. The author has an hindex of 27, co-authored 119 publications receiving 2263 citations. Previous affiliations of Bhavik Anil Patel include Royal School of Mines & Imperial College London.
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Simple and rapid determination of serotonin and catecholamines in biological tissue using high-performance liquid chromatography with electrochemical detection
TL;DR: It was found that the storage of tissue samples at -20 degrees C caused losses of dopamine and serotonin and the total time of analysis was substantially reduced resulting in a sample preparation and assay time of 15-20 min.
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3D printable conductive materials for the fabrication of electrochemical sensors: A mini review
TL;DR: In this article, the authors present recent developments in the use of conductive materials that can be printed using additive manufacturing (3D printing), enabling the development of mass-produced electrochemical sensors of varying geometries.
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Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolites
Mari L. Lund,Kristoffer L. Egerod,Maja S. Engelstoft,Oksana Dmytriyeva,Elvar Theodorsson,Bhavik Anil Patel,Thue W. Schwartz +6 more
TL;DR: Nutrient metabolites apparently do not stimulate EC cells of the small intestine directly but through a paracrine mechanism involving GLP-1 secreted from neighboring enteroendocrine cells, in contrast to colonic EC cells, which are able to sense a multitude of different metabolites generated by the gut microbiota as well as gut hormones, including GLp-1.
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Enteric glia mediate neuron death in colitis through purinergic pathways that require connexin-43 and nitric oxide.
TL;DR: The results show that the activation of glial cells in the context of neuroinflammation kills enteric neurons, and the glial response to inflammatory mediators might contribute to the development of motility disorders.
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In vitro continuous amperometric monitoring of 5-hydroxytryptamine release from enterochromaffin cells of the guinea pig ileum
TL;DR: The 5- HT oxidation current increased in the presence of the serotonin transporter (SERT) inhibitor, fluoxetine (1 microM), providing evidence that the oxidation current was associated with 5-HT.