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Biaoyang Lin
Researcher at Zhejiang California International NanoSystems Institute
Publications - 83
Citations - 4472
Biaoyang Lin is an academic researcher from Zhejiang California International NanoSystems Institute. The author has contributed to research in topics: Prostate cancer & Gene. The author has an hindex of 36, co-authored 77 publications receiving 4025 citations. Previous affiliations of Biaoyang Lin include Zhejiang University & University of Washington.
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Journal Article
Prostate-localized and Androgen-regulated Expression of the Membrane-bound Serine Protease TMPRSS2
Biaoyang Lin,Camari Ferguson,James T. White,Shunyou Wang,Robert L. Vessella,Lawrence D. True,Leroy Hood,Peter S. Nelson +7 more
TL;DR: Results suggest that TMPRSS2 may play a role in prostate carcinogenesis and should be investigated as a diagnostic or therapeutic target for the management of prostate cancers.
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The program of androgen-responsive genes in neoplastic prostate epithelium
Peter S. Nelson,Nigel J. Clegg,Hugh Arnold,Camari Ferguson,Michael Bonham,James F. White,Leroy Hood,Biaoyang Lin +7 more
TL;DR: The results identify previously uncharacterized and unsuspected genes whose expression levels are directly or indirectly regulated by androgens and provide a comprehensive temporal view of the transcriptional program of human androgen-responsive cells.
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Identification of cavities on protein surface using multiple computational approaches for drug binding site prediction
TL;DR: This work adds four more methods Fpocket, GHECOM, ConCavity and POCASA to further improve the prediction success rate of MetaPocket, and constructs a non-redundant dataset of drug-target complexes with known structure from DrugBank, DrugPort and PDB database to predict drug binding sites.
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Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach.
Dong Ding,Xiaoyan Lou,Dasong Hua,Wei Yu,Lisha Li,Jun Wang,Feng Gao,Na Zhao,Guoping Ren,Lanjuan Li,Biaoyang Lin,Biaoyang Lin +11 more
TL;DR: A massive anchored parallel sequencing method using next-generation sequencing to isolate and sequence HBV integrants and identified 8 genes that were recurrent target genes by HBV integration, suggesting a clonal expansion model in HCC development.
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The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis
Xuefeng Fang,Jae-Geun Yoon,Lisha Li,Wei Yu,Jiaofang Shao,Dasong Hua,Shu-Mei Zheng,Leroy Hood,David R. Goodlett,Gregory Foltz,Biaoyang Lin,Biaoyang Lin +11 more
TL;DR: It is shown that knockdown of the SOX2 gene in LN229 GBM cells reduces cell proliferation and colony formation, and thatSOX2 down regulates BEX1 and BEX2, two genes with tumor suppressor activity in GBM, potentially creating a bistable system in G BM cells.