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Bimaljit S. Sandhu
Researcher at St Mary's Hospital
Publications - 40
Citations - 1033
Bimaljit S. Sandhu is an academic researcher from St Mary's Hospital. The author has contributed to research in topics: Pancreatitis & Smoking cessation. The author has an hindex of 13, co-authored 38 publications receiving 776 citations. Previous affiliations of Bimaljit S. Sandhu include VCU Medical Center & Mayo Clinic.
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Journal ArticleDOI
Mechanisms of CFTR functional variants that impair regulated bicarbonate permeation and increase risk for pancreatitis but not for cystic fibrosis.
Jessica LaRusch,Jinsei Jung,Ignacio J. General,Michele D. Lewis,Hyun Woo Park,Randall E. Brand,Andres Gelrud,Michelle A. Anderson,Peter A. Banks,Darwin L. Conwell,Christopher Lawrence,Joseph Romagnuolo,John Baillie,Samer Alkaade,Gregory A. Cote,Timothy B. Gardner,Stephen T. Amann,Adam Slivka,Bimaljit S. Sandhu,Amy Aloe,Michelle L. Kienholz,Dhiraj Yadav,M. Michael Barmada,Ivet Bahar,Min Goo Lee,David C. Whitcomb +25 more
TL;DR: WNK1-SPAK pathway-activated increases in CFTR bicarbonate permeability are altered by CFTRBD variants through multiple mechanisms, and molecular dynamics simulations suggest physical restriction of the CFTR channel and altered dynamic channel regulation.
Journal ArticleDOI
Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities.
Jorge D. Machicado,Stephen T. Amann,Michelle A. Anderson,Judah Abberbock,Stuart Sherman,Darwin L. Conwell,Gregory A. Cote,Vikesh K. Singh,Michele D. Lewis,Samer Alkaade,Bimaljit S. Sandhu,Nalini M. Guda,Thiruvengadam Muniraj,Gong Tang,John Baillie,Randall E. Brand,Timothy B. Gardner,Andres Gelrud,Chris E. Forsmark,Peter A. Banks,Adam Slivka,C. Mel Wilcox,David C. Whitcomb,Dhiraj Yadav +23 more
TL;DR: Constant pain, pain-related disability/unemployment, current smoking, and concurrent co-morbidities significantly affect the QOL in CP patients, according to multivariable linear regression models.
PANCREAS, BILIARY TRACT, AND LIVER Chronic Pancreatitis Pain Pattern and Severity Are Independent of Abdominal Imaging Findings
C. Mel Wilcox,Dhiraj Yadav,Tian Ye,Timothy B. Gardner,Andres Gelrud,Bimaljit S. Sandhu,Michele D. Lewis,Samer Al-Kaade,Gregory A. Cote,Chris E. Forsmark,Nalini M. Guda,Darwin L. Conwell,Peter A. Banks,Thiruvengadam Muniraj,Joseph Romagnuolo,Randall E. Brand,Adam Slivka,Stuart Sherman,Stephen R. Wisniewski,David C. Whitcomb,Michelle A. Anderson +20 more
TL;DR: Mechanisms that determine patterns and severity of pain in patients with chronic pancreatitis are largely independent of structural variants observed by abdominal imaging techniques.
Journal ArticleDOI
Patient and Disease Characteristics Associated With the Presence of Diabetes Mellitus in Adults With Chronic Pancreatitis in the United States
Melena D. Bellin,David C. Whitcomb,Judah Abberbock,Stuart Sherman,Bimaljit S. Sandhu,Timothy B. Gardner,Michelle A. Anderson,Michele D. Lewis,Samer Alkaade,Vikesh K. Singh,John Baillie,Peter A. Banks,Darwin L. Conwell,Gregory A. Cote,Nalini M. Guda,Thiruvengadam Muniraj,Gong Tang,Randall E. Brand,Andres Gelrud,Stephen T. Amann,Chris E. Forsmark,C. Mel Wilcox,Adam Slivka,Dhiraj Yadav +23 more
TL;DR: In this large multicenter cohort of patients with CP, exocrine insufficiency, calcifications, and pancreas surgery conveyed higher odds of having DM, however, the traditional ‘type 2 DM’ risk factors of obesity and family history were similarly important in conveying risk for DM.
Journal ArticleDOI
Management of ascites in cirrhosis.
TL;DR: Large volume paracentesis and transjugular intrahepatic porto-systemic shunts are useful in managing patients with refractory ascites and liver transplant is the only way to improve survival in ascites caused by cirrhosis.