B
Bin Ji
Researcher at Wuhan University of Science and Technology
Publications - 320
Citations - 7185
Bin Ji is an academic researcher from Wuhan University of Science and Technology. The author has contributed to research in topics: Chemistry & Computer science. The author has an hindex of 30, co-authored 228 publications receiving 4569 citations. Previous affiliations of Bin Ji include Academy of Military Medical Sciences & Nantong University.
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Journal ArticleDOI
Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls
Masahiro Maruyama,Hitoshi Shimada,Tetsuya Suhara,Hitoshi Shinotoh,Bin Ji,Jun Maeda,Ming-Rong Zhang,John Q. Trojanowski,Virginia M.-Y. Lee,Maiko Ono,Kazuto Masamoto,Harumasa Takano,Naruhiko Sahara,Naruhiko Sahara,Nobuhisa Iwata,Nobuyuki Okamura,Shozo Furumoto,Yukitsuka Kudo,Qing Chang,Takaomi C. Saido,Akihiko Takashima,Jada Lewis,Ming Kuei Jang,Ichio Aoki,Hiroshi Ito,Makoto Higuchi +25 more
TL;DR: A class of tau ligands, phenyl/pyridinyl-butadienyl-benzothiazoles/benZothiazoliums (PBBs), for visualizing diverse tau inclusions in brains of living patients with AD or non-AD tauopathies and animal models of these disorders are developed.
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A review on in situ phytoremediation of mine tailings.
TL;DR: In this review, the background, concepts and applications of phytoremediation are comprehensively discussed, and proper amendments used to improve the physical, chemical and biological properties of mine tailings are systematically reviewed and compared.
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Aerobic denitrification: A review of important advances of the last 30 years
TL;DR: Aerobic denitrifiers tend to work efficiently at 25 ~ 37°C and pH 7 ~ 8, when dissolved oxygen concentration is 3 ~ 5 mg/L and C/N load ratio is 5 ~ 10, and the periplasmic nitrate reductase is vital for aerobic denItrifiers and NapA gene may be the proof of aerobic denitrification.
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Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography
Jun Maeda,Bin Ji,Toshiaki Irie,Takami Tomiyama,Masahiro Maruyama,Takashi Okauchi,Matthias Staufenbiel,Nobuhisa Iwata,Maiko Ono,Takaomi C. Saido,Kazutoshi Suzuki,Hiroshi Mori,Makoto Higuchi,Tetsuya Suhara +13 more
TL;DR: The results support the usefulness of the small animal-dedicated PET system in conjunction with high-specific radioactivity probes and appropriate Tg models not only for clarifying the mechanistic properties of amyloidogenesis in mouse models but also for preclinical tests of emerging diagnostic and therapeutic approaches to AD.
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Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies.
Bin Ji,Jun Maeda,Makoto Sawada,Maiko Ono,Takashi Okauchi,Motoki Inaji,Ming-Rong Zhang,Kazutoshi Suzuki,Kiyoshi Ando,Matthias Staufenbiel,John Q. Trojanowski,Virginia M.-Y. Lee,Makoto Higuchi,Tetsuya Suhara +13 more
TL;DR: Together, PBR expressions in astrocytes and microglia reflect beneficial and deleterious glial reactions, respectively, in diverse neurodegenerative disorders including AD, pointing to new applications of PBR imaging for monitoring the impact of gliosis on the pathogenesis and treatment of AD.