Binbin Xi

TL;DR: In this paper, a Cas12a-based RT-PCR combined with CRISPR on-site rapid detection system (RT-CORDS) platform was used to detect the key mutations in SARS-CoV-2 variants, such as 69/70 deletion, N501Y, and D614G.

TL;DR: The AutoVEM tool developed in the present study could complete all mutations detections, haplotypes classification, haplotype subgroup epidemic trends and candidate key mutations analysis for 131,576 SARS-CoV-2 genome sequences in 18 hours on a 1 core CPU and 2GB RAM computer.

TL;DR: Zhang et al. as discussed by the authors selected the key mutations of SARS-CoV-2, including D614G and A222V of S protein and Q57H of ORF3a protein, to conduct molecular dynamics simulation and analysis on the structures of the mutant proteins.

TL;DR: Wang et al. as mentioned in this paper developed a flexible automated tool to analyze candidate key mutations and epidemic trends for any virus, which would become a standard process for virus analysis based on genome sequences in the future.

TL;DR: Wang et al. as discussed by the authors developed a flexible automated tool to analyze candidate key mutations and epidemic trends for any virus, which would become a standard process for virus analysis based on genome sequences in the future.