Bingyu Yan

TL;DR: A new potent dCas9–TAD, named d Cas9–TV, is developed through plant cell-based screens that confers far stronger transcriptional activation of single or multiple target genes than the routinely used dCas 9–VP64 activator in both plant and mammalian cells.

TL;DR: In this paper, the authors found that the complement system was one of the intracellular pathways most highly induced by SARS-CoV-2 infection in lung epithelial cells.

TL;DR: This paper showed that complement triggers contraction of helper T responses by inducing intrinsic expression of the vitamin D (VitD) receptor and the VitD-activating enzyme CYP27B1, permitting T cells to both activate and respond to VitD.

TL;DR: A comprehensive map of the host cell-pathogen interactome in EBV-associated cancers is presented, uncover novel points of interaction between a common oncovirus and the human genome and identify novel regulatory nodes and druggable targets for individualized EBV and cancer-specific therapies.

TL;DR: The findings indicate that HVC events observed in RNA-sequencing libraries from SARS-CoV2 infected cells are extremely rare and are likely artifacts arising from either random template switching of reverse-transcriptase and/or sequence alignment errors.