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Biswa Choudhury
Researcher at University of California, San Diego
Publications - 70
Citations - 3469
Biswa Choudhury is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Sialic acid & Mutant. The author has an hindex of 27, co-authored 64 publications receiving 2920 citations. Previous affiliations of Biswa Choudhury include University of San Diego & University of Georgia.
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Journal ArticleDOI
Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens
Katharine M. Ng,Jessica A. Ferreyra,Steven K. Higginbottom,Jonathan B. Lynch,Purna C. Kashyap,Purna C. Kashyap,Smita Gopinath,Natasha Naidu,Biswa Choudhury,Bart C. Weimer,Denise M. Monack,Justin L. Sonnenburg +11 more
TL;DR: The data show that antibiotic-induced disruption of the resident microbiota and subsequent alteration in mucosal carbohydrate availability are exploited by these two distantly related enteric pathogens in a similar manner, which suggests new therapeutic approaches for preventing diseases caused by antibiotic-associated pathogens.
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The human milk oligosaccharide disialyllacto-N-tetraose prevents necrotising enterocolitis in neonatal rats
Evelyn Jantscher-Krenn,Monica Zherebtsov,Caroline Nissan,Kerstin Goth,Yigit S. Guner,Natasha Naidu,Biswa Choudhury,Anatoly Grishin,Henri R. Ford,Lars Bode +9 more
TL;DR: HMO reduce NEC in neonatal rats and the effects are highly structure specific, and if these results translate to NEC in humans, DSLNT could be used to prevent or treat NEC in formula-fed infants, and its concentration in the mother's milk could serve as a biomarker to identify breast- fed infants at risk of developing this disorder.
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Acidic pH increases airway surface liquid viscosity in cystic fibrosis
Xiao Xiao Tang,Lynda S. Ostedgaard,Mark J. Hoegger,Thomas O. Moninger,Philip H. Karp,James D. McMenimen,Biswa Choudhury,Ajit Varki,David A. Stoltz,Michael J. Welsh +9 more
TL;DR: Airway surface liquid collected from newborn piglets and ASL on cultured airway epithelia revealed that the viscosity of CF ASL was increased relative to that of non-CF ASL, suggesting that acidic pH influences mucin electrostatic interactions.
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Identification, Characterization and Immunogenicity of an O-Antigen Capsular Polysaccharide of Francisella tularensis
Michael A. Apicella,Deborah M. B. Post,Andrew C. Fowler,Bradley D. Jones,Jed A. Rasmussen,Jason Hunt,Sayaka Imagawa,Biswa Choudhury,Thomas J. Inzana,Tamara M. Maier,Dara W. Frank,Thomas C. Zahrt,Kathryn Chaloner,Michael P. Jennings,Molly K. McLendon,Bradford W. Gibson +15 more
TL;DR: It is demonstrated that F. tularensis produces an O-antigen capsule that may be the basis of a future vaccine and mass spectrometry, compositional analysis and NMR indicate that the capsule is composed of a polymer of the tetrasaccharide repeat.
Journal ArticleDOI
Identification of cptA, a PmrA-Regulated Locus Required for Phosphoethanolamine Modification of the Salmonella enterica Serovar Typhimurium Lipopolysaccharide Core
Rita Tamayo,Biswa Choudhury,Alecia N. Septer,Massimo Merighi,Russell W. Carlson,John S. Gunn +5 more
TL;DR: It is demonstrated that the PmrA-regulated STM4118 (cptA) gene is necessary for the addition of pEtN to the LPS core, and neither pmrC nor cptA plays a dramatic role in antimicrobial peptide resistance in vitro or virulence in the mouse model.