Biswajit Chakraborty

TL;DR: Administration of aqueous extract of C. longa has immunotherapeutic properties along with its ability to ameliorate hepatotoxicity in CCl4 intoxicated Swiss albino mice is suggested to offer significant protection from these damaging actions of CCl3 on the non specific host response in the peritoneal macrophages.

TL;DR: The intrinsic properties of noble metal NPs (gold and silver) as well as the mechanism of their potential antitumor activity are addressed, seen that AuNPs and AgNPs modulate the reactive oxygen species (ROS) and reactive nitrogen Species (RNS) production, suppressing the antioxidant system of cells (TAMs).

TL;DR: Toxicity studies revealed a relationship between AgNPs and immune function, and the protumorigenic cytokines TNF-α, IL-6 and IL-1β were also assayed in AgNP-MSA-treated and non-treated fibrosarcoma groups, and these cytokines were found to be downregulated after treatment with AgNP -MSA.

TL;DR: Polar fractions of Tinospora cordifolia stem parts contain major bioactive compounds, which directly act on peritoneal macrophages and have been found to boost the non-specific host defenses of the immune system.

TL;DR: The result obtained suggests that bioactive principles of these plants can be used particularly against these multidrug resistant bacteria of clinical origin.