Bohui Li

TL;DR: The particular strengths of TCMSP are the composition of the large number of herbal entries, and the ability to identify drug-target networks and drug-disease networks, which will help revealing the mechanisms of action of Chinese herbs, uncovering the nature ofTCM theory and developing new herb-oriented drugs.

TL;DR: The mechanism of efficiency of Radix Curcumae formula for the prevention of CCVD is explained, and the potential targets of the Chinese medicines are predicted, which facilitates to elucidate the compatible mechanism of the complex prescription, i.e., "jun-chen-zuo-shi".

TL;DR: The action mechanism of these three important Chinese herbs for the treatment of CVD is uncovered, by generating and identifying both their active ingredients and novel targets specifically related to CVD, which clarifies some of the common conceptions in TCM, and thus provides clues to modernize such specific herbal medicines.

TL;DR: The overall data suggest that the medicinal herbs function by indirectly suppressing the virus proliferation via regulating the immune systems in hosts, and also, by directly inhibiting virus proliferation through targeting viral proteins essential for the viral life cycle.

TL;DR: An integrated systems pharmacology platform combining pharmacokinetics, chemogenomics, pharmacology and systems biology data through computational methods is reported, which results in a superior output of information for systematic drug design strategies for complex diseases.