B
Brad Bettman
Researcher at Pacific Biosciences
Publications - 2
Citations - 3553
Brad Bettman is an academic researcher from Pacific Biosciences. The author has contributed to research in topics: Single molecule real time sequencing & Oligonucleotide. The author has an hindex of 2, co-authored 2 publications receiving 3376 citations.
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Journal ArticleDOI
Real-Time DNA Sequencing from Single Polymerase Molecules
John Eid,Adrian Fehr,Jeremy Gray,Khai Luong,John Lyle,Geoff Otto,Paul Peluso,David R. Rank,Primo Baybayan,Brad Bettman,Arkadiusz Bibillo,Keith Bjornson,Bidhan Chaudhuri,Fred Christians,Ronald L. Cicero,Sonya Clark,Ravindra V. Dalal,Alex DeWinter,John Dixon,Mathieu Foquet,Alfred Gaertner,Paul Hardenbol,Cheryl Heiner,Kevin Hester,David P. Holden,Gregory J. Kearns,Xiangxu Kong,Ronald Kuse,Yves Lacroix,Steven Lin,Paul Lundquist,Congcong Ma,Patrick Marks,Mark Maxham,Devon Murphy,Insil Park,Thang Pham,Michael Phillips,Joy Roy,Robert Sebra,Gene Shen,Jon M. Sorenson,Austin B. Tomaney,Kevin Travers,Mark Trulson,John Vieceli,Jeffrey Wegener,Dawn Wu,Alicia Yang,Denis Zaccarin,Peter Zhao,Frank Zhong,Jonas Korlach,Stephen Turner +53 more
TL;DR: Single-molecule, real-time sequencing data obtained from a DNA polymerase performing uninterrupted template-directed synthesis using four distinguishable fluorescently labeled deoxyribonucleoside triphosphates (dNTPs) are presented.
Journal ArticleDOI
Parallel confocal detection of single molecules in real time
Paul Lundquist,Cheng F Zhong,Peiqian Zhao,Austin B. Tomaney,Paul Peluso,John Dixon,Brad Bettman,Yves Lacroix,Kwo Deborah Pao-Tung,Etienne McCullough,Mark Maxham,Kevin Hester,Paul McNitt,Donald M Grey,Carlos Henriquez,Mathieu Foquet,Stephen Turner,Denis Zaccarin +17 more
TL;DR: The confocal detection principle is extended to a highly parallel optical system that continuously analyzes thousands of concurrent sample locations and is demonstrated to detect and identify single fluorescent molecules from each of several thousand independent confocal volumes in real time.