Brad J. Thacker

TL;DR: The discovery of swine HEV not only has implications for HEV vaccine development, diagnosis, and biology, but also raises a potential public health concern for zoonosis or xenozoonosis following xenotransplantation with pig organs.

TL;DR: Results indicate that M. hyopneumoniae infection potentiates PRRSV-induced disease and lesions, which is important with respect to the control of respiratory disease in pigs and has implications in elucidating the potential contribution of mycoplasmas in the pathogenesis of viral infections of other species, including humans.

TL;DR: The development of two modified indirect enzyme-linked immunosorbent assays (ELISAs) based on cell-culture-propagated PCV2 and an ORF2 ELISA based on recombinant major capsid protein are reported, which should accelerate the understanding of the host immune response to PCV 2 and facilitate the development of prevention and control strategies by elucidating the ecology ofPCV2 within swine populations.

TL;DR: The increased production of proinflammatory cytokines in vivo and in vitro associated with concurrent M. hyopneumoniae and PRRSV infection may play a role in the increased rates of pneumonia associated with PR RSV infection.

TL;DR: The results of this study found that while pigs infected with both agents exhibited more severe clinical disease, the relationship between the two pathogens lacked the profound potentiation found with dual infection with M. hyopneumoniae and PRRSV.