B
Brahm Goldstein
Researcher at Oregon Health & Science University
Publications - 72
Citations - 5924
Brahm Goldstein is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Intracranial pressure & Traumatic brain injury. The author has an hindex of 24, co-authored 72 publications receiving 5304 citations. Previous affiliations of Brahm Goldstein include University of Medicine and Dentistry of New Jersey.
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International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics.
TL;DR: The current criteria used to define SIRS and sepsis in adults were modified to incorporate pediatric physiologic variables appropriate for the following subcategories of children: newborn, neonate, infant, child, and adolescent.
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Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial.
Simon Nadel,Brahm Goldstein,Mark D. Williams,Heidi J. Dalton,Mark J. Peters,William L. Macias,Shamel Abd-Allah,Howard Levy,Robinette Angle,Dazhe Wang,David P. Sundin,Brett P. Giroir +11 more
TL;DR: Although the RESOLVE trial did not record any efficacy of DrotAA in children with severe sepsis, serious bleeding events were similar between groups and the overall safety profile acceptable, except in children younger than 60 days.
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Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial
Michael Levin,Peter A. Quint,Brahm Goldstein,Phil Barton,John S. Bradley,Sam D. Shemie,Timothy Yeh,Sun Sook Kim,Daniel P Cafaro,Patrick J. Scannon,Brett P. Giroir +10 more
TL;DR: The results overall indicate that rBPI21 is beneficial in decreasing complications of meningococcal disease as well as improving outcome in all primary outcome variables.
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An automatic beat detection algorithm for pressure signals
TL;DR: An automatic detection algorithm for pressure signals that locates the first peak following each heart beat that is called the percussion peak in intracranial pressure (ICP) signals and the systolic peak in arterial blood pressure (ABP) and pulse oximetry (SpO/sub 2/) signals is designed.
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Uncoupling of the autonomic and cardiovascular systems in acute brain injury
TL;DR: It is concluded that severity of neurological injury and outcome are inversely associated with HR and BP variability and there is direct evidence for cardiovascular and autonomic uncoupling in acute brain injury with complete uncouplings during brain death.