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Bram F. Coolen
Researcher at University of Amsterdam
Publications - 80
Citations - 1260
Bram F. Coolen is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 19, co-authored 59 publications receiving 951 citations. Previous affiliations of Bram F. Coolen include Academic Medical Center & Eindhoven University of Technology.
Papers
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Journal ArticleDOI
PCA-based groupwise image registration for quantitative MRI.
Wyke Huizinga,Dirk H. J. Poot,Dirk H. J. Poot,Jean-Marie Guyader,Remy Klaassen,Bram F. Coolen,M. van Kranenburg,R.J. Van Geuns,André Uitterdijk,Mathias Polfliet,Mathias Polfliet,Jef Vandemeulebroucke,Jef Vandemeulebroucke,Alexander Leemans,Wiro J. Niessen,Wiro J. Niessen,Stefan Klein +16 more
TL;DR: The groupwise registration method with a similarity measure based on PCA is the preferred technique for compensating misalignments in qMRI.
Journal ArticleDOI
Distribution of lipid-based nanoparticles to infarcted myocardium with potential application for MRI-monitored drug delivery.
Leonie E. M. Paulis,Tessa Geelen,Michael T. Kuhlmann,Bram F. Coolen,Michael Schäfers,Klaas Nicolay,Gustav J. Strijkers +6 more
TL;DR: In this article, the distribution pattern of differently sized long-circulating lipid-based nanoparticles, namely micelles (~15 nm) and liposomes (~100 nm), in a mouse model of myocardial infarction was characterized.
Journal ArticleDOI
Three-dimensional T1 mapping of the mouse heart using variable flip angle steady-state MR imaging.
Bram F. Coolen,Tessa Geelen,Leonie E. M. Paulis,Arno Nauerth,Klaas Nicolay,Gustav J. Strijkers +5 more
TL;DR: This study shows that 3D T1 mapping in the mouse heart is feasible and can be used to monitor regional changes in myocardial T1, particularly in relation to pathology and in contrast‐enhanced experiments to estimate local concentrations of (targeted) contrast agent.
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Evaluation of ultrasmall superparamagnetic iron-oxide (USPIO) enhanced MRI with ferumoxytol to quantify arterial wall inflammation.
Loek P. Smits,Feiko Tiessens,Kang H. Zheng,Erik S.G. Stroes,Aart J. Nederveen,Bram F. Coolen +5 more
TL;DR: Ferumoxytol is selectively taken up by atherosclerotic plaques and can thus be used for carotid USPIO-MRI, and may visualize different pathophysiological aspects of plaque inflammation.
Journal ArticleDOI
Three-dimensional quantitative T1 and T2 mapping of the carotid artery: Sequence design and in vivo feasibility.
Bram F. Coolen,Dirk H. J. Poot,Madieke I. Liem,Loek P. Smits,Shan Gao,Gyula Kotek,Stefan Klein,Aart J. Nederveen +7 more
TL;DR: A novel three‐dimensional T1 and T2 mapping protocol for the carotid artery is presented and it is shown that the protocol can be applied to both the EMT and non‐ EMT phases of the heart.