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Brenda Barnes
Researcher at Vanderbilt University Medical Center
Publications - 8
Citations - 1025
Brenda Barnes is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Population & Antigen. The author has an hindex of 6, co-authored 8 publications receiving 959 citations. Previous affiliations of Brenda Barnes include Vanderbilt University.
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Journal ArticleDOI
Epidemiology of Invasive Streptococcus pneumoniae Infections in the United States, 1995-1998: Opportunities for Prevention in the Conjugate Vaccine Era
Katherine Robinson,Wendy Baughman,G. Rothrock,Nancy L. Barrett,Margaret Pass,Catherine Lexau,Barbara Damaske,Karen Stefonek,Brenda Barnes,Jan E. Patterson,Elizabeth R. Zell,Anne Schuchat,Cynthia G. Whitney +12 more
TL;DR: Young children, elderly persons, and black persons of all ages are disproportionately affected by invasive pneumococcal disease, and current ACIP recommendations do not address a subset of persons aged 18 to 64 years but do include those at highest risk for death from invasive pneumonia.
Journal ArticleDOI
Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States
Ben J. Metcalf,Sopio Chochua,Robert E. Gertz,Zhongya Li,Hollis Walker,T. Tran,Paulina A. Hawkins,Anita Glennen,Ruth Lynfield,Y. Li,Lesley McGee,Bernard Beall,Art Reingold,S. Brooks,H. Randel,Lisa Miller,B. White,Deborah Aragon,Meghan Barnes,J. Sadlowski,Sue Petit,Matthew L. Cartter,C. Marquez,M. Wilson,Monica M. Farley,Stepy Thomas,Amy Tunali,W. Baughman,Lee H. Harrison,J. Benton,T. Carter,Rosemary Hollick,K. Holmes,A. Riner,Corinne Holtzman,Richard Danila,K. MacInnes,Karen Scherzinger,Kathy Angeles,Joseph Bareta,L. Butler,S. Khanlian,R. Mansmann,Megin Nichols,Nancy M. Bennett,S. Zansky,S. Currenti,Suzanne McGuire,Ann Thomas,M. Schmidt,Jamie Thompson,Tasha Poissant,William Schaffner,Brenda Barnes,K. Leib,K. Dyer,L. McKnight,R. Gierke,Olivia Almendares,J. Hudson,L. McGlone,Gayle Fischer Langley +61 more
TL;DR: WGS-based antimicrobial phenotype prediction was an informative alternative to BDT for invasive pneumococci and correctly predicted penicillin-binding protein types and common resistance determinants.
Journal ArticleDOI
Short-read whole genome sequencing for determination of antimicrobial resistance mechanisms and capsular serotypes of current invasive Streptococcus agalactiae recovered in the USA
Benjamin J. Metcalf,Sopio Chochua,Robert E. Gertz,Paulina A. Hawkins,Jessica N. Ricaldi,Zhongya Li,Hollis Walker,T. Tran,J. Rivers,S. Mathis,Delois Jackson,Anita Glennen,Ruth Lynfield,Lesley McGee,Bernard Beall,Art Reingold,S. Brooks,H. Randel,Lisa Miller,B. White,Deborah Aragon,Meghan Barnes,J. Sadlowski,Sue Petit,Matthew L. Cartter,C. Marquez,M. Wilson,Monica M. Farley,Stepy Thomas,Amy Tunali,W. Baughman,Lee H. Harrison,J. Benton,T. Carter,Rosemary Hollick,K. Holmes,A. Riner,Corinne Holtzman,Richard Danila,K. MacInnes,Karen Scherzinger,Kathy Angeles,Joseph Bareta,L. Butler,S. Khanlian,R. Mansmann,Megin Nichols,Nancy M. Bennett,S. Zansky,S. Currenti,Suzanne McGuire,Ann Thomas,M. Schmidt,Jamie Thompson,Tasha Poissant,William Schaffner,Brenda Barnes,K. Leib,K. Dyer,L. McKnight,Olivia Almendares,J. Hudson,L. McGlone,Cynthia G. Whitney,Stephanie J. Schrag,Gayle Fischer Langley +65 more
TL;DR: The WGS-based assignment of iGBS resistance features and serotypes is an accurate substitute for phenotypic testing.
Journal ArticleDOI
Homotypic antibody responses to fresh clinical isolates of human immunodeficiency virus.
David C. Montefiori,Jiying Zhou,Brenda Barnes,Douglas F. Lake,Eban M. Hersh,Yasuhiko Masuho,Lewis B. Lefkowitz +6 more
TL;DR: It is suggested that it is common for neutralization-resistant HIV-1 variants to appear during the course of infection, and that all or most antigens of these variants are capable of escaping antibody recognition.
Journal ArticleDOI
Aggregated antibiograms and monitoring of drug-resistant Streptococcus pneumoniae.
Chris A. Van Beneden,Catherine Lexau,Wendy Baughman,Brenda Barnes,Nancy M. Bennett,P. Maureen Cassidy,Margaret Pass,Lisa B. Gelling,Nancy L. Barrett,Elizabeth R. Zell,Cynthia G. Whitney +10 more
TL;DR: Community-specific antimicrobial susceptibility data may help monitor trends among drug-resistant Streptococcus pneumoniae and guide empiric therapy, and antibiograms offer limited data on isolates with intermediate and high-level penicillin resistance and isolates resistant to other agents.