B
Brett Garner
Researcher at University of Wollongong
Publications - 117
Citations - 7111
Brett Garner is an academic researcher from University of Wollongong. The author has contributed to research in topics: Apolipoprotein E & Ceramide. The author has an hindex of 45, co-authored 117 publications receiving 6313 citations. Previous affiliations of Brett Garner include Linköping University & Prince of Wales Medical Research Institute.
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Journal ArticleDOI
Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease.
Karen E. Murphy,Karen E. Murphy,Amanda M. Gysbers,Sarah K. Abbott,Sarah K. Abbott,Nahid Tayebi,Woojin S. Kim,Woojin S. Kim,Ellen Sidransky,Anthony Cooper,Anthony Cooper,Brett Garner,Brett Garner,Glenda M. Halliday,Glenda M. Halliday +14 more
TL;DR: Glucocerebrosidase deficits in sporadic Parkinson's disease are related to the abnormal accumulation of α-synuclein and are associated with substantial alterations in lysosomal chaperone-mediated autophagy pathways and lipid metabolism.
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Oxidation of High Density Lipoproteins II. EVIDENCE FOR DIRECT REDUCTION OF LIPID HYDROPEROXIDES BY METHIONINE RESIDUES OF APOLIPOPROTEINS AI AND AII
TL;DR: It is concluded that the oxidation of specific Met residues of apoAI and apoAII to Met(O) plays a significant role in the 2-electron reduction of hydroperoxides of cholesteryl esters and phosphatidylcholine associated with human HDL.
Journal ArticleDOI
Characterization of the kynurenine pathway in human neurons.
Gilles J. Guillemin,Karen M. Cullen,Chai K. Lim,George A. Smythe,Brett Garner,Vimal Kapoor,Osamu Takikawa,Bruce J. Brew +7 more
TL;DR: The kynurenine pathway is characterized in human neurons and the human SK-N-SH neuroblastoma cell line and it is found that the kyn Laurenine pathway enzymes were variably expressed.
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Oxidation of High Density Lipoproteins I. FORMATION OF METHIONINE SULFOXIDE IN APOLIPOPROTEINS AI AND AII IS AN EARLY EVENT THAT ACCOMPANIES LIPID PEROXIDATION AND CAN BE ENHANCED BY α-TOCOPHEROL
Brett Garner,Paul K. Witting,A. Reginald Waldeck,Julie K. Christison,Mark J. Raftery,Roland Stocker +5 more
TL;DR: The results indicate that the earliest stages of HDL oxidation are accompanied by the oxidation of specific methionine residues in apoAI and apoAII and that in the absence of co-antioxidants, α-TOH can promote this process.
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Polypyrrole-heparin composites as stimulus-responsive substrates for endothelial cell growth.
Brett Garner,A. Georgevich,A. Georgevich,A.J. Hodgson,A.J. Hodgson,L Liu,L Liu,Gordon G. Wallace +7 more
TL;DR: Electrochemically synthesized composites comprising heparin and the electrically conducting polymer polypyrrole had a shelf life of at least 2 years postautoclaving and were found to be excellent substrates for the growth of human endothelial cells.