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Brian Buck

Researcher at University of Alberta

Publications -  110
Citations -  5408

Brian Buck is an academic researcher from University of Alberta. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 28, co-authored 80 publications receiving 4220 citations. Previous affiliations of Brian Buck include University of California, Los Angeles & University of Alberta Hospital.

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Journal ArticleDOI

Impact of collateral flow on tissue fate in acute ischaemic stroke

TL;DR: The data suggest that angiographic collateral grade and penumbral volume interactively shape tissue fate in patients undergoing endovascular recanalisation therapy, and provide complementary information about residual blood flow that may help guide treatment decision making in acute cerebral ischaemia.
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Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.

Michael D. Hill, +776 more
- 14 Mar 2020 - 
TL;DR: Nerinetide did not improve the proportion of patients achieving good clinical outcomes after endovascular thrombectomy compared with patients receiving placebo, and this trial is registered with ClinicalTrials.gov, NCT02930018.
Journal Article

Impact of collateral flow on tissue fate in acute ischaemic stroke. Commentary

TL;DR: In this article, the authors used functional MRI (fMRI) data to investigate whether hippocampal activation during a memory task can predict cognitive decline in individuals with mild cognitive impairment (MCI), as measured by change in Clinical Dementia Rating Sum-of-Boxes (CDR-SB).
Journal ArticleDOI

Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data

Bruce C.V. Campbell, +1296 more
- 01 Jan 2019 - 
TL;DR: Estimated ischaemic core volume was independently associated with functional independence and functional improvement but did not modify the treatment benefit of endovascular thrombectomy over standard medical therapy for improved functional outcome.