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Brian D. Muegge
Researcher at Washington University in St. Louis
Publications - 19
Citations - 33687
Brian D. Muegge is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Microbiome & Gut flora. The author has an hindex of 13, co-authored 17 publications receiving 28053 citations.
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Journal ArticleDOI
QIIME allows analysis of high-throughput community sequencing data.
J. Gregory Caporaso,Justin Kuczynski,Jesse Stombaugh,Kyle Bittinger,Frederic D. Bushman,Elizabeth K. Costello,Noah Fierer,Antonio Gonzalez Peña,Julia K. Goodrich,Jeffrey I. Gordon,Gavin A. Huttley,Scott T. Kelley,Dan Knights,Jeremy E. Koenig,Ruth E. Ley,Catherine A. Lozupone,Daniel McDonald,Brian D. Muegge,Meg Pirrung,Jens Reeder,Joel Sevinsky,Peter J. Turnbaugh,William A. Walters,Jeremy Widmann,Tanya Yatsunenko,Jesse R. Zaneveld,Rob Knight,Rob Knight +27 more
TL;DR: An overview of the analysis pipeline and links to raw data and processed output from the runs with and without denoising are provided.
Journal ArticleDOI
Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans
Brian D. Muegge,Justin Kuczynski,Dan Knights,Jose C. Clemente,Antonio Gonzalez,Luigi Fontana,Luigi Fontana,Bernard Henrissat,Rob Knight,Rob Knight,Jeffrey I. Gordon +10 more
TL;DR: The value of characterizing vertebrate gut microbiomes to understand host evolutionary histories at a supraorganismal level is illustrated by shotgun sequencing of microbial community DNA and targeted sequencing of bacterial 16S ribosomal RNA genes.
Journal ArticleDOI
Persistent gut microbiota immaturity in malnourished Bangladeshi children
Sathish Subramanian,Sayeeda Huq,Tanya Yatsunenko,Rashidul Haque,Mustafa Mahfuz,Mohammed Ashraful Alam,Amber Benezra,Amber Benezra,Joseph DeStefano,Martin Meier,Brian D. Muegge,Michael J. Barratt,Laura G. VanArendonk,Qunyuan Zhang,Michael A. Province,William A. Petri,Tahmeed Ahmed,Jeffrey I. Gordon +17 more
TL;DR: The results indicate that SAM is associated with significant relative microbiota immaturity that is only partially ameliorated following two widely used nutritional interventions.
Journal ArticleDOI
Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications.
Pelin Yilmaz,Pelin Yilmaz,Renzo Kottmann,Dawn Field,Rob Knight,Rob Knight,James R. Cole,Linda A. Amaral-Zettler,Jack A. Gilbert,Jack A. Gilbert,Jack A. Gilbert,Ilene Karsch-Mizrachi,Anjanette Johnston,Guy Cochrane,Robert Vaughan,Christopher I. Hunter,Joonhong Park,Norman Morrison,Philippe Rocca-Serra,Peter Sterk,Manimozhiyan Arumugam,Mark J. Bailey,Laura K. Baumgartner,Bruce W. Birren,Martin J. Blaser,Vivien Bonazzi,Timothy F. Booth,Peer Bork,Frederic D. Bushman,Pier Luigi Buttigieg,Pier Luigi Buttigieg,Patrick S. G. Chain,Patrick S. G. Chain,Patrick S. G. Chain,Emily S. Charlson,Elizabeth K. Costello,Heather Huot-Creasy,Peter Dawyndt,Todd Z. DeSantis,Noah Fierer,Jed A. Fuhrman,Rachel E. Gallery,Dirk Gevers,Richard A. Gibbs,Inigo San Gil,Antonio Gonzalez,Jeffrey I. Gordon,Robert P. Guralnick,Wolfgang Hankeln,Wolfgang Hankeln,Sarah K. Highlander,Philip Hugenholtz,Janet K. Jansson,Janet K. Jansson,Andrew L. Kau,Scott T. Kelley,Jerry Kennedy,Dan Knights,Omry Koren,Justin Kuczynski,Nikos C. Kyrpides,Robert Larsen,Christian L. Lauber,Teresa M. Legg,Ruth E. Ley,Catherine A. Lozupone,Wolfgang Ludwig,Donna Lyons,Eamonn Maguire,Barbara A. Methé,Folker Meyer,Brian D. Muegge,Sara Nakielny,Karen E. Nelson,Diana R. Nemergut,Josh D. Neufeld,Lindsay K. Newbold,Anna Oliver,Norman R. Pace,Giriprakash Palanisamy,Jörg Peplies,Joseph F. Petrosino,Lita M. Proctor,Elmar Pruesse,Elmar Pruesse,Christian Quast,Jeroen Raes,Sujeevan Ratnasingham,Jacques Ravel,David A. Relman,David A. Relman,Susanna Assunta-Sansone,Patrick D. Schloss,Lynn M. Schriml,Rohini Sinha,Michelle I. Smith,Erica Sodergren,Aymé Spor,Jesse Stombaugh,James M. Tiedje,Doyle V. Ward,George M. Weinstock,Doug Wendel,Owen White,Andrew S. Whiteley,Andreas Wilke,Jennifer R. Wortman,Tanya Yatsunenko,Frank Oliver Glöckner,Frank Oliver Glöckner +109 more
TL;DR: To establish a unified standard for describing sequence data and to provide a single point of entry for the scientific community to access and learn about GSC checklists, the minimum information about any (x) sequence is presented (MIxS).
Journal ArticleDOI
The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins
Nathan P. McNulty,Tanya Yatsunenko,Ansel Hsiao,Jeremiah J. Faith,Brian D. Muegge,Andrew L. Goodman,Bernard Henrissat,Raish Oozeer,Stéphanie Cools-Portier,Guillaume Gobert,Christian Chervaux,Dan Knights,Catherine A. Lozupone,Rob Knight,Alexis E. Duncan,James R. Bain,Michael J. Muehlbauer,Christopher B. Newgard,Andrew C. Heath,Jeffrey I. Gordon +19 more
TL;DR: The findings show that mice containing a sequenced model human gut microbiome can serve as part of a preclinical discovery pipeline designed to identify the effects of existing or new bacterial species with purported health benefits on the gut microbiomes of various human populations.