B
Brian Litt
Researcher at University of Pennsylvania
Publications - 246
Citations - 19050
Brian Litt is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Epilepsy & Ictal. The author has an hindex of 62, co-authored 222 publications receiving 16733 citations. Previous affiliations of Brian Litt include Hospital of the University of Pennsylvania & Philadelphia University.
Papers
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Journal ArticleDOI
Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics
Dae-Hyeong Kim,Jonathan Viventi,Jason J. Amsden,Jianliang Xiao,Leif Vigeland,Yun-Soung Kim,Justin A. Blanco,Bruce Panilaitis,Eric S. Frechette,Diego Contreras,David L. Kaplan,Fiorenzo G. Omenetto,Yonggang Huang,Keh-Chih Hwang,Mitchell R. Zakin,Brian Litt,John A. Rogers +16 more
TL;DR: A material strategy for a type of bio-interfaced system that relies on ultrathin electronics supported by bioresorbable substrates of silk fibroin that provides new capabilities for implantable and surgical devices is described.
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Flexible, foldable, actively multiplexed, high-density electrode array for mapping brain activity in vivo
Jonathan Viventi,Dae-Hyeong Kim,Leif Vigeland,Eric S. Frechette,Justin A. Blanco,Yun-Soung Kim,Andrew E. Avrin,Vineet Tiruvadi,Suk Won Hwang,Ann C. Vanleer,Drausin Wulsin,Kathryn A. Davis,Casey E. Gelber,Larry A. Palmer,Jan Van der Spiegel,Jian Wu,Jianliang Xiao,Yonggang Huang,Diego Contreras,John A. Rogers,Brian Litt +20 more
TL;DR: This system is used to record spatial properties of cat brain activity in vivo, including sleep spindles, single-trial visual evoked responses and electrographic seizures, and it is found that seizures may manifest as recurrent spiral waves that propagate in the neocortex.
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Materials for multifunctional balloon catheters with capabilities in cardiac electrophysiological mapping and ablation therapy
Dae-Hyeong Kim,Nanshu Lu,Roozbeh Ghaffari,Yun-Soung Kim,Stephen P. Lee,Lizhi Xu,Jian Wu,Rak-Hwan Kim,Jizhou Song,Zhuangjian Liu,Jonathan Viventi,Bassel de Graff,Brian Elolampi,Moussa Mansour,Marvin J. Slepian,Suk Won Hwang,Joshua D. Moss,Sang Min Won,Younggang Huang,Brian Litt,John A. Rogers +20 more
TL;DR: This paper describes a solution based on materials that integrate directly with the thin elastic membranes of otherwise conventional balloon catheters, to provide diverse, multimodal functionality suitable for clinical use.
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Epileptic seizures may begin hours in advance of clinical onset: a report of five patients.
Brian Litt,Rosana Esteller,Rosana Esteller,J. Echauz,J. Echauz,M. D'Alessandro,Rachel Shor,Thomas R. Henry,Page B. Pennell,Charles M. Epstein,Roy A.E. Bakay,Marc Dichter,George Vachtsevanos +12 more
TL;DR: It is suggested that epileptic seizures may begin as a cascade of electrophysiological events that evolve over hours and that quantitative measures of preseizure electrical activity could possibly be used to predict seizures far in advance of clinical onset.
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High‐frequency oscillations and seizure generation in neocortical epilepsy
TL;DR: The finding that high-frequency epileptiform oscillations are highly localized in the seizure onset zone, both before and temporally removed from seizure onset, points to an important role for neuromodulatory circuits, probably involving the thalamus, in mechanisms underlying seizure generation in neocortical epilepsy.