Brian O'Sullivan

TL;DR: Overall survival was slightly better in patients who had preoperative radiotherapy than in those who had postoperative treatment, and the size and anatomical site of the tumour was also significant risk factors in multivariate analysis.

TL;DR: AJCC's 8th edition of the Staging manual, Head and Neck Section, introduced significant modifications from the prior 7th edition as discussed by the authors, including the reorganization of skin cancer (other than melanoma and Merkel cell carcinoma) from a general chapter for the entire body to a head and neck-specific cutaneous malignancies chapter; division of cancer of the pharynx into 3 separate chapters; changes to the tumor (T) categories for oral cavity, skin, and nasopharynx; and the addition of extranodal cancer extension to lymph

TL;DR: New guidelines are provided for the appropriate application of drug therapies used in the maintenance of pulmonary function to improve and extend the lives of all individuals with cystic fibrosis.

TL;DR: Comparison of the different types of altered radiotherapy suggests that hyperfractionation has the greatest benefit, whereas the benefit on nodal control was less pronounced.

TL;DR: It is reported that dying tumor cells use the apoptotic process to generate potent growth-stimulating signals to stimulate the repopulation of tumors undergoing radiotherapy, and activated caspase 3, a key executioner in apoptosis, is involved in the growth stimulation.