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Brian P. Hedlund
Researcher at University of Nevada, Las Vegas
Publications - 176
Citations - 9279
Brian P. Hedlund is an academic researcher from University of Nevada, Las Vegas. The author has contributed to research in topics: Biology & Metagenomics. The author has an hindex of 39, co-authored 150 publications receiving 7395 citations. Previous affiliations of Brian P. Hedlund include University of Washington & University of Nevada, Reno.
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Journal ArticleDOI
Insights into the phylogeny and coding potential of microbial dark matter
Christian Rinke,Patrick Schwientek,Alexander Sczyrba,Alexander Sczyrba,Natalia Ivanova,Iain Anderson,Jan Fang Cheng,Aaron E. Darling,Aaron E. Darling,Stephanie Malfatti,Brandon K. Swan,Esther A. Gies,Jeremy A. Dodsworth,Brian P. Hedlund,Georgios Tsiamis,Stefan M. Sievert,Wen Tso Liu,Jonathan A. Eisen,Steven J. Hallam,Nikos C. Kyrpides,Ramunas Stepanauskas,Edward M. Rubin,Philip Hugenholtz,Tanja Woyke +23 more
TL;DR: This study applies single-cell genomics to target and sequence 201 archaeal and bacterial cells from nine diverse habitats belonging to 29 major mostly uncharted branches of the tree of life and provides a systematic step towards a better understanding of biological evolution on the authors' planet.
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Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea
Robert M. Bowers,Nikos C. Kyrpides,Ramunas Stepanauskas,Miranda Harmon-Smith,Devin F. R. Doud,T. B. K. Reddy,Frederik Schulz,Jessica K. Jarett,Adam R. Rivers,Adam R. Rivers,Emiley A. Eloe-Fadrosh,Susannah G. Tringe,Susannah G. Tringe,Natalia Ivanova,Alex Copeland,Alicia Clum,Eric D. Becraft,Rex R. Malmstrom,Bruce W. Birren,Mircea Podar,Peer Bork,George M. Weinstock,George M. Garrity,Jeremy A. Dodsworth,Shibu Yooseph,Granger G. Sutton,Frank Oliver Gloeckner,Jack A. Gilbert,William C. Nelson,Steven J. Hallam,Sean P. Jungbluth,Sean P. Jungbluth,Thijs J. G. Ettema,Scott Tighe,Konstantinos T. Konstantinidis,Wen Tso Liu,Brett J. Baker,Thomas Rattei,Jonathan A. Eisen,Brian P. Hedlund,Katherine D. McMahon,Noah Fierer,Rob Knight,Robert D. Finn,Guy Cochrane,Ilene Karsch-Mizrachi,Gene W. Tyson,Christian Rinke,Alla Lapidus,Folker Meyer,Pelin Yilmaz,Donovan H. Parks,A. M. Eren,Lynn M. Schriml,Jillian F. Banfield,Philip Hugenholtz,Tanja Woyke +56 more
TL;DR: Two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences are presented, including the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum information about a Metagenome-Assembled Genomes (MIMAG), including estimates of genome completeness and contamination.
Journal ArticleDOI
Polycyclic aromatic hydrocarbon degradation by a new marine bacterium, Neptunomonas naphthovorans gen. nov., sp. nov
TL;DR: Differences in morphologic, physiologic, and genotypic differences between the new strains and the oceanospirilla justify the creation of a novel genus and species, Neptunomonas naphthovorans.
Journal ArticleDOI
A korarchaeal genome reveals insights into the evolution of the Archaea.
James Elkins,Mircea Podar,David E. Graham,Kira S. Makarova,Yuri I. Wolf,Lennart Randau,Brian P. Hedlund,Céline Brochier-Armanet,Victor Kunin,Iain Anderson,Alla Lapidus,Eugene Goltsman,Kerrie Barry,Eugene V. Koonin,Philip Hugenholtz,Nikos C. Kyrpides,Gerhard Wanner,Paul G. Richardson,Martin Keller,Karl O. Stetter,Karl O. Stetter +20 more
TL;DR: The initial characterization of a member of the Korarchaeota with the proposed name, “Candidatus Kor Archaeum cryptofilum,” which exhibits an ultrathin filamentous morphology is reported, suggesting that the organism relies on a simple mode of peptide fermentation for carbon and energy and lacks the ability to synthesize de novo purines, CoA, and several other cofactors.
Journal ArticleDOI
Anaerobic naphthalene degradation by microbial pure cultures under nitrate-reducing conditions
Karl J. Rockne,Joanne C. Chee-Sanford,Robert A. Sanford,Brian P. Hedlund,James T. Staley,Stuart E. Strand +5 more
TL;DR: Nitrate consumption, along with the results from the 14C radiolabel study, are consistent with the oxidation of naphthalene coupled to denitrification for Nap-3-1 and nitrate reduction to nitrite for NAP-4, the first report the authors know of that demonstrates nitrate-dependent anaerobic degradation and mineralization of nphthalene by pure cultures.