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Broto Chakrabarty
Researcher at International Institute of Information Technology, Hyderabad
Publications - 12
Citations - 228
Broto Chakrabarty is an academic researcher from International Institute of Information Technology, Hyderabad. The author has contributed to research in topics: Protein structure & Ankyrin repeat. The author has an hindex of 5, co-authored 9 publications receiving 159 citations.
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Journal ArticleDOI
NAPS: Network Analysis of Protein Structures.
Broto Chakrabarty,Nita Parekh +1 more
TL;DR: A web server for network based analysis of protein structures, NAPS, that facilitates quantitative and qualitative analysis of residue–residue interactions in single chains, protein complex, modelled protein structures and trajectories and provides insights into structure-function relationship.
Journal ArticleDOI
NAPS update: network analysis of molecular dynamics data and protein-nucleic acid complexes.
TL;DR: NAPS as discussed by the authors is a method of choice to gain insights in understanding protein structure, folding and function, which is an invaluable tool with widespread applications such as analyzing subtle conformational changes and flexibility regions in proteins, dynamic correlation analysis across distant regions for allosteric communications, in drug design to reveal alternative binding pockets for drugs, etc.
Journal ArticleDOI
Identifying tandem Ankyrin repeats in protein structures
Broto Chakrabarty,Nita Parekh +1 more
TL;DR: Eigen spectra profile of a protein structure graph exhibits a unique repetitive profile for contiguous repeating units enabling the detection of the repeat region and the repeat type, which is especially useful in correctly identifying new members of a repeat family.
Journal ArticleDOI
PRIGSA: protein repeat identification by graph spectral analysis.
Broto Chakrabarty,Nita Parekh +1 more
TL;DR: The efficacy of the approach is shown on eight repeat families annotated in UniProt, comprising of both solenoid and nonsolenoid repeats with varied secondary structure architecture and repeat lengths and the performance compared with two repeat identification methods.
Proceedings ArticleDOI
Analysis of graph centrality measures for identifying Ankyrin repeats
Broto Chakrabarty,Nita Parekh +1 more
TL;DR: The spectral analysis being computationally efficient, the analysis of the principal eigen spectra of the adjacency matrix of proteins containing Ankyrin (ANK) repeats, the most commonly occurring structural motifs in proteins are presented.