B
Bruce H. Howard
Researcher at Laboratory of Molecular Biology
Publications - 36
Citations - 11732
Bruce H. Howard is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Transfection & Gene. The author has an hindex of 20, co-authored 36 publications receiving 11703 citations.
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Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.
TL;DR: A series of recombinant genomes which directed expression of the enzyme chloramphenicol acetyltransferase (CAT) in mammalian cells provided a uniquely convenient system for monitoring the expression of foreign DNAs in tissue culture cells.
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The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection
TL;DR: The results indicate that the Rous sarcoma virus LTR can direct synthesis of high levels of functional mRNA and has a wide expression range.
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High efficiency DNA-mediated transformation of primate cells
TL;DR: Tissue culture cells from several mammalian species, including three primate lines, were transfected with recombinant vectors carrying Escherichia coli xanthine-guanine phosphoribosyltransferase or Tn5 aminoglycoside phosphotransferase dominant selectable markers to establish stable transformation frequencies.
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Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.
TL;DR: The findings suggest that the tandem repeat elements may interact with host-specific molecules and, furthermore, may constitute one of the elements determining the host range of these eukaryotic viruses.
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Expression of recombinant plasmids in mammalian cells Is enhanced by sodium butyrate
TL;DR: The results demonstrate that butyrate affects the early stages of gene activity following DNA uptake at least two levels, and expression of integrated recombinant plasmid genes is reinducible by a second treatment five weeks after initial exposure to this agent.