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Bruce Neal
Researcher at The George Institute for Global Health
Publications - 620
Citations - 109123
Bruce Neal is an academic researcher from The George Institute for Global Health. The author has contributed to research in topics: Population & Blood pressure. The author has an hindex of 108, co-authored 561 publications receiving 87213 citations. Previous affiliations of Bruce Neal include National Institutes of Health & University of the Western Cape.
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A one-quarter reduction in the salt content of bread can be made without detection.
TL;DR: A one-quarter reduction in the sodium content of white bread can be delivered over a short time period, while maintaining consumer acceptance, according to a single-blind, randomized, controlled trial.
Journal ArticleDOI
Effect of Salt Substitution on Cardiovascular Events and Death.
Bruce Neal,Yangfeng Wu,Xiangxian Feng,Ruijuan Zhang,Yuhong Zhang,Jingpu Shi,Jianxin Zhang,Maoyi Tian,Liping Huang,Zhifang Li,Yan Yu,Yi Zhao,Bo Zhou,Jixin Sun,Yishu Liu,Xuejun Yin,Zhixin Hao,Jie Yu,Ka-Chun Li,Xinyi Zhang,Peifen Duan,Faxuan Wang,Bing Ma,Weiwei Shi,Gian Luca Di Tanna,Sandrine Stepien,Sana Shan,Sallie-Anne Pearson,Nicole Li,Lijing L. Yan,Darwin R. Labarthe,Paul Elliott +31 more
TL;DR: Among persons who had a history of stroke or were 60 years of age or older and had high blood pressure, the rates of stroke, major cardiovascular events, and death from any cause were lower with the salt substitute than with regular salt.
Journal ArticleDOI
Lowering Blood Pressure Reduces Renal Events in Type 2 Diabetes
Bastiaan E. de Galan,Bastiaan E. de Galan,Vlado Perkovic,Toshiharu Ninomiya,Avinesh Pillai,Anushka Patel,Alan Cass,Bruce Neal,Neil R Poulter,Stephen B. Harrap,Carl Erik Mogensen,Mark E. Cooper,Michel Marre,Bryan Williams,Pavel Hamet,Giuseppe Mancia,Mark Woodward,Paul Glasziou,Diederick E. Grobbee,Stephen MacMahon,John Chalmers +20 more
TL;DR: BP-lowering treatment with perindopril-indapamide administered routinely to individuals with type 2 diabetes provides important renoprotection, even among those with initial BP <120/70 mmHg, and a BP threshold below which renal benefit is lost is not identified.
Journal ArticleDOI
Effects of a Perindopril-Based Blood Pressure-Lowering Regimen on the Risk of Recurrent Stroke According to Stroke Subtype and Medical History. The PROGRESS Trial
N. Chapman,Rachel R. Huxley,Craig S. Anderson,Marie-Germaine Bousser,John Chalmers,S. Colman,Stephen M. Davis,Geoffrey A. Donnan,Stephen MacMahon,Bruce Neal,Charles Warlow,Mark Woodward +11 more
TL;DR: Beneficial effects of a perindopril-based treatment regimen were observed for all stroke types and all major clinical subgroups studied and suggest that effective blood pressure–lowering therapy should be routinely considered for all patients with a history of cerebrovascular events.
Priority medicines for Europe and the world
TL;DR: Echoing the trend seen in Europe, much of the rest of the world is moving in a similar direction, and the 2013 update calls for pharmaceutical researchers to adjust their research and development efforts to account for this shifting demography.