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Bruce Poppe

Researcher at Ghent University Hospital

Publications -  124
Citations -  24986

Bruce Poppe is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 45, co-authored 119 publications receiving 22635 citations. Previous affiliations of Bruce Poppe include Ghent University.

Papers
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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Jo Vandesompele, +6 more
- 18 Jun 2002 - 
TL;DR: The normalization strategy presented here is a prerequisite for accurate RT-PCR expression profiling, which opens up the possibility of studying the biological relevance of small expression differences.
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Breast-Cancer Risk in Families with Mutations in PALB2

Antonis C. Antoniou, +47 more
- 06 Aug 2014 - 
TL;DR: The data suggest the breast-cancer risk for PALB2 mutation carriers may overlap with that for BRCA1 mutation carriers, and loss-of-function mutations in PALB1 are an important cause of hereditary breast cancer.
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Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

Timothy R. Rebbeck, +261 more
- 07 Apr 2015 - 
TL;DR: In this paper, the relationship between specific mutations in BRCA1 and cancer risk has been investigated and limited information about the relationship has been available about specific mutations for specific mutations.
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Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Catherine M. Phelan, +443 more
- 01 May 2017 - 
TL;DR: Integrated analyses of genes and regulatory biofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous EOC.
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PHF6 mutations in T-cell acute lymphoblastic leukemia

Pieter Van Vlierberghe, +34 more
- 01 Apr 2010 - 
TL;DR: PHF6 is identified as a new X-linked tumor suppressor in T-ALL and a strong genetic interaction between PHF6 loss and aberrant expression of TLX transcription factors in the pathogenesis of this disease is pointed to.