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Showing papers by "Bruce W. Birren published in 2020"

Journal Article•DOI•
A comparative genomics multitool for scientific discovery and conservation

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Diane P. Genereux1, Aitor Serres2, Joel Armstrong3, Jeremy Johnson3, Voichita D. Marinescu, Eva Murén, David Juan4, Gill Bejerano, Nicholas R. Casewell, Leona G. Chemnick, Joana Damas, Federica Di Palma, Mark Diekhans, Ian T. Fiddes, Manuel Garber, Vadim N. Gladyshev, Linda Goodman, Wilfried Haerty, Marlys L. Houck, Robert Hubley, Teemu Kivioja, Klaus-Peter Koepfli, Lukas F. K. Kuderna, Eric S. Lander, Jennifer R. S. Meadows, William J. Murphy, Will Nash, Hyun Ji Noh, Martin T. Nweeia, Andreas R. Pfenning, Katherine S. Pollard, David A. Ray, Beth Shapiro, Arian F.A. Smit, Mark S. Springer, Cynthia C. Steiner, Ross Swofford, Jussi Taipale, Emma C. Teeling, Jason Turner-Maier, Jessica Alföldi, Bruce W. Birren, Oliver A. Ryder, Harris A. Lewin, Benedict Paten, Tomas Marques-Bonet, Kerstin Lindblad-Toh, Elinor K. Karlsson4 •
Broad Institute1, Pompeu Fabra University2, University of California, Santa Cruz3, University of Massachusetts Amherst4
12 Nov 2020-Nature
TL;DR: It is found that regions of reduced genetic diversity are more abundant in species at a high risk of extinction, discern signals of evolutionary selection at high resolution and provide insights from individual reference genomes.
Abstract: A whole-genome alignment of 240 phylogenetically diverse species of eutherian mammal-including 131 previously uncharacterized species-from the Zoonomia Project provides data that support biological ...

172 citations