Brunella Grigolo

TL;DR: It is highlighted that, despite its encouraging results, the clinical approach of Bone Tissue Engineering has not taken place on a large scale yet, due to the need of more in depth studies, its high manufacturing costs and the difficulty to obtain regulatory approval.

TL;DR: The data indicate that human chondrocytes seeded on HYAFF 11 express and produce collagen type II and aggrecan and downregulate the production of collagen type I, providing an in vitro demonstration for the therapeutic potential of HYAff 11 as a delivery vehicle in a tissue-engineered approach towards the repair of articular cartilage defects.

TL;DR: A new approach investigating the healing of rabbit cartilage by means of autologous chondrocytes seeded on a hyaluronan derivative referred to as Hyaff-11 is described, demonstrating the efficacy of this hyAluronan-based scaffold for autologously chondROcytes transplantation.

TL;DR: The one-step technique is an alternative for cartilage repair, permitting improved functional scores and overcoming the drawbacks of previous techniques, suggesting the future in osteochondral repair may represent the future.

TL;DR: In this article, a Hyalograft C scaffold was used for arthroscopic chondrocyte implantation in the ankle for posttraumatic talar dome lesions, type II or IIA.