B
Bryan Beattie
Researcher at University of Toronto
Publications - 40
Citations - 5842
Bryan Beattie is an academic researcher from University of Toronto. The author has contributed to research in topics: Gene & Functional genomics. The author has an hindex of 9, co-authored 40 publications receiving 5642 citations.
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Journal ArticleDOI
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae
Nevan J. Krogan,Gerard Cagney,Gerard Cagney,Haiyuan Yu,Gouqing Zhong,Xinghua Guo,Alexandr Ignatchenko,Joyce Li,Shuye Pu,Nira Datta,Aaron Tikuisis,Thanuja Punna,José M. Peregrín-Alvarez,Michael Shales,Xin Zhang,Michael Davey,Mark D. Robinson,Alberto Paccanaro,James E. Bray,Anthony Sheung,Bryan Beattie,Dawn Richards,Veronica Canadien,Atanas Iliev Lalev,Frank Mena,Peter D Wong,Andrei Starostine,Myra M. Canete,James Vlasblom,Samuel Wu,Chris Orsi,Sean R. Collins,Shamanta Chandran,Robin Haw,Jennifer J. Rilstone,Kiran Gandi,Natalie J. Thompson,Gabe Musso,Peter St Onge,Shaun Ghanny,Mandy H. Y. Lam,Gareth Butland,Amin M. Altaf-Ul,Shigehiko Kanaya,Ali Shilatifard,Erin K. O'Shea,Jonathan S. Weissman,C. James Ingles,Timothy P. Hughes,John Parkinson,Mark Gerstein,Shoshana J. Wodak,Andrew Emili,Jack Greenblatt +53 more
TL;DR: T tandem affinity purification was used to process 4,562 different tagged proteins of the yeast Saccharomyces cerevisiae to identify protein–protein interactions, which will help future studies on individual proteins as well as functional genomics and systems biology.
Journal ArticleDOI
Interaction network containing conserved and essential protein complexes in Escherichia coli
Gareth Butland,José M. Peregrín-Alvarez,Joyce Li,Wehong Yang,Xiaochun Yang,Veronica Canadien,Andrei Starostine,Dawn Richards,Bryan Beattie,Nevan J. Krogan,Michael Davey,John Parkinson,John Parkinson,Jack Greenblatt,Andrew Emili +14 more
TL;DR: Insight is provided into the function of previously uncharacterized bacterial proteins and the overall topology of a microbial interaction network, the core components of which are broadly conserved across Prokaryota.
Journal ArticleDOI
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II.
Nevan J. Krogan,Minkyu Kim,Amy Hin Yan Tong,Ashkan Golshani,Gerard Cagney,Veronica Canadien,Dawn Richards,Bryan Beattie,Andrew Emili,Charles Boone,Ali Shilatifard,Stephen Buratowski,Jack Greenblatt +12 more
TL;DR: It is shown here that yeast Set2 copurifies with RNA polymerase II (RNAPII), and Chromatin immunoprecipitation analyses demonstrated that Set2 and histone H3 Lys36 methylation are associated with the coding regions of several genes that were tested and correlate with active transcription.
Journal ArticleDOI
High-Definition Macromolecular Composition of Yeast RNA-Processing Complexes
Nevan J. Krogan,Wen-Tao Peng,Gerard Cagney,Mark D. Robinson,Robin Haw,Gouqing Zhong,Xinghua Guo,Xin Zhang,Veronica Canadien,Dawn Richards,Bryan Beattie,Atanas Iliev Lalev,Wen Zhang,Armaity P. Davierwala,Sanie Mnaimneh,Andrei Starostine,Aaron Tikuisis,Jörg Grigull,Nira Datta,James E. Bray,Timothy P. Hughes,Andrew Emili,Jack Greenblatt +22 more
TL;DR: This study systematically identified and estimated the relative abundance of stably associated polypeptides and RNA species using a combination of gel densitometry, protein mass spectrometry, and oligonucleotide microarray hybridization.
Journal ArticleDOI
A Panoramic View of Yeast Noncoding RNA Processing
Wen Tao Peng,Mark D. Robinson,Sanie Mnaimneh,Nevan J. Krogan,Gerard Cagney,Quaid Morris,Armaity P. Davierwala,Jörg Grigull,Xueqi Yang,Wen Zhang,Nicholas Mitsakakis,Owen Ryan,Nira Datta,Vladimir Jojic,Chris Pal,Veronica Canadien,Dawn Richards,Bryan Beattie,Lani F. Wu,Steven J. Altschuler,Sam T. Roweis,Brendan J. Frey,Andrew Emili,Jack Greenblatt,Timothy P. Hughes +24 more
TL;DR: A global view of yeast noncoding RNA processing is presented and it is confirmed that many currently uncharacterized yeast proteins are involved in biogenesis of nonc coding RNA.