B
Bulent Arman Aksoy
Researcher at Medical University of South Carolina
Publications - 53
Citations - 26176
Bulent Arman Aksoy is an academic researcher from Medical University of South Carolina. The author has contributed to research in topics: T cell & BioPAX : Biological Pathways Exchange. The author has an hindex of 24, co-authored 53 publications receiving 19600 citations. Previous affiliations of Bulent Arman Aksoy include Memorial Sloan Kettering Cancer Center & Icahn School of Medicine at Mount Sinai.
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The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
Ethan Cerami,Jianjiong Gao,Ugur Dogrusoz,Benjamin Gross,Selcuk Onur Sumer,Bulent Arman Aksoy,Anders Jacobsen,Caitlin Byrne,Michael Heuer,Erik G. Larsson,Yevgeniy Antipin,Boris Reva,Arthur P. Goldberg,Chris Sander,Nikolaus Schultz +14 more
TL;DR: The cBio Cancer Genomics Portal significantly lowers the barriers between complex genomic data and cancer researchers who want rapid, intuitive, and high-quality access to molecular profiles and clinical attributes from large-scale cancer genomics projects and empowers researchers to translate these rich data sets into biologic insights and clinical applications.
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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
Jianjiong Gao,Bulent Arman Aksoy,Ugur Dogrusoz,Gideon Dresdner,Benjamin Gross,S. Onur Sumer,Yichao Sun,Anders Jacobsen,Rileen Sinha,Erik Larsson,Ethan Cerami,Chris Sander,Nikolaus Schultz +12 more
TL;DR: A practical guide to the analysis and visualization features of the cBioPortal for Cancer Genomics, which makes complex cancer genomics profiles accessible to researchers and clinicians without requiring bioinformatics expertise, thus facilitating biological discoveries.
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Emerging landscape of oncogenic signatures across human cancers
Giovanni Ciriello,Martin L. Miller,Bulent Arman Aksoy,Yasin Senbabaoglu,Nikolaus Schultz,Chris Sander +5 more
TL;DR: This work distilled thousands of genetic and epigenetic features altered in cancers to ∼500 selected functional events (SFEs) and derived a hierarchical classification of 3,299 TCGA tumors from 12 cancer types, indicating the presence of different oncogenic processes.
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Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis.
Alexandra Snyder,Alexandra Snyder,Tavi Nathanson,Samuel Funt,Samuel Funt,Arun Ahuja,Jacqueline Buros Novik,Matthew D. Hellmann,Matthew D. Hellmann,Eliza Chang,Bulent Arman Aksoy,Hikmat Al-Ahmadie,Erik Yusko,Marissa Vignali,Sharon Benzeno,Mariel Elena Boyd,Meredith Maisie Moran,Gopa Iyer,Gopa Iyer,Harlan Robins,Elaine R. Mardis,Taha Merghoub,Jeff Hammerbacher,Jonathan E. Rosenberg,Dean F. Bajorin,Dean F. Bajorin +25 more
TL;DR: The results demonstrate the complex nature of immune response to checkpoint blockade and the compelling need for greater interrogation and data integration of both host and tumor factors.
Journal ArticleDOI
Pathway Commons 2019 Update: integration, analysis and exploration of pathway data.
Igor Rodchenkov,Özgün Babur,Augustin Luna,Bulent Arman Aksoy,Jeffrey V. Wong,Dylan Fong,Max Franz,Metin Can Siper,Manfred Cheung,Michael Wrana,Harsh Mistry,Logan Mosier,Jonah Dlin,Qizhi Wen,Caitlin O'Callaghan,Wanxin Li,Geoffrey Elder,Peter T. Smith,Christian Dallago,Christian Dallago,Ethan Cerami,Benjamin Gross,Ugur Dogrusoz,Emek Demir,Gary D. Bader,Chris Sander +25 more
TL;DR: Pathway Commons as mentioned in this paper is an integrated resource of publicly available information about biological pathways including biochemical reactions, assembly of biomolecular complexes, transport and catalysis events and physical interactions involving proteins, DNA, RNA, and small molecules (e.g. metabolites and drug compounds).