Author
C.A.M.G. Cramers
Bio: C.A.M.G. Cramers is an academic researcher from Eindhoven University of Technology. The author has contributed to research in topics: Reversed-phase chromatography & Column chromatography. The author has an hindex of 35, co-authored 102 publications receiving 3216 citations.
Papers published on a yearly basis
Papers
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TL;DR: The parameters proposed quantitatively characterize the RP-HPLC stationary phases and provide a rational explanation for the differences in retention patterns of individual columns observed when applying the conventional empirical testing methods are proposed.
189 citations
TL;DR: The results of the various tests, however, are not always qualified to describe the properties of columns for reversed phase liquid chromatography (RPLC) is still not a straightforward process as mentioned in this paper.
164 citations
TL;DR: The applicability of empirical based, thermodynamically based and test methods based on a retention model to characterise silica-based reversed phase stationary phases, as well as the influence of the eluent composition on the LC analysis of basic substances is described.
123 citations
TL;DR: It is shown that the spectral scan speed of the time-of-flight mass spectrometer is high enough for very fast separations and the quality of the recorded spectra and the comparison with library spectra was very high.
116 citations
TL;DR: In this paper, it was shown theoretically that for an isothermal analysis, the relationship of the retention time to the column diameter is determined by the column pressure drop and varies between z 1 for high plate number columns and z ǫ 2 for situations of low pressure drop.
115 citations
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1,992 citations
TL;DR: Increased utilization of mechanically stable synthetic matrices particularly silica gel as a solid support and its surface modification by impregnation of organic ligands directly or covalent grafting through spacer unit for extractive concentration of trace elements are highlighted in the present article.
860 citations
Book•
23 Jul 1999TL;DR: Size exclusion chromatography separates macromolecules according to their hydrodynamic volume and has become the dominant method for the determination of molecular weight or mass distribution (MWD or MMD) of synthetic polymers.
Abstract: PROBLEM TO BE SOLVED: To perform molecular weight measurement and separation of a fluorine containing organic substance slightly soluble in a general organic solvent by means of size exclusion chromatography by using a solvent containing dichloro pentafluoropropane as a mobile phase and using polymethyl methacrylate with a known molecular weight as a molecular weight measurement standard specimen. SOLUTION: As a mobile phase. a solvent containing HCFC225 such as a solvent containing only HCFC225 and a mixture solvent containing HCFC225 and other solvents are available. HCFC225 is selected from one or more kinds of substances selected from chlorinated fluorinated hydrocarbons with a molecular formula represented by C3 HF3 Cl2 . As the HCFC225, several kinds of isomers with the same molecular formula and different structures are known, however, HCFC225ca (CF3 CF2 CHCl2 ), HCFC225cb (CF2 ClCF2 CFHC1), and a mixture of them are desirable. As a molecular weight measurement standard specimen, polymethyl methacrylate with a known molecular weight is used.
502 citations
TL;DR: This review discusses the column efficiency of HILIC materials in relation to solute and stationary phase structures, as well as comparisons between particle-packed and monolithic columns.
394 citations
TL;DR: In recent years, matrix assisted laser desorption/ionization time-of-flight (MALDI-TOF) has become a routine analytical tool for the structural analysis of polymers, complementing NMR and other traditional techniques as mentioned in this paper.
387 citations